Epithelial cells require apical–basal plasma membrane polarity to carry out crucial vectorial
transport functions and cytoplasmic polarity to generate different cell progenies for tissue …

Fluorescence microscopy is one of the most powerful tools for elucidating the cellular
functions of proteins and other molecules. In many cases, the function of a molecule can be …

To form epithelial organs cells must polarize and generate de novo an apical domain and
lumen. Epithelial polarization is regulated by polarity complexes that are hypothesized to …

Experiments using mammalian epithelial cell lines have elucidated biosynthetic and
recycling pathways for apical and basolateral plasma-membrane proteins, and have …

Vesicle‐mediated transcellular transport or simply “transcytosis” is a cellular process used to
shuttle macromolecules such as lipoproteins, antibodies, and albumin from one surface of a …

The MHC class I-related receptor, FcRn, plays a central role in regulating the serum levels of
IgG. FcRn is expressed in endothelial cells, suggesting that these cells may be involved in …

Myosin Va is associated with discrete vesicle populations in a number of cell types, but little
is known of the function of myosin Vb. Yeast two-hybrid screening of a rabbit parietal cell …

In the early days of epithelial cell biology, researchers working with kidney and/or intestinal
epithelial cell lines and with hepatocytes described the biosynthetic and recycling routes …

As the primary physiological barrier, intestinal epithelial cells regulate the transportation of
oral therapeutic agents including nanomedicines which significantly improves the …

The adherens junction (AJ) and tight junction (TJ) are key regulators of epithelial polarity
and barrier function. Loss of epithelial phenotype is accompanied by endocytosis of AJs and …