Reactive oxygen species (ROS) are highly reactive oxygen-containing molecules generated
as natural byproducts during cellular processes, including metabolism. Under normal …

Ferroptosis is a distinct lipid peroxidation-dependent form of necrotic cell death. This
process has been increasingly contemplated as a new target for cancer therapy because of …

Selenocysteine (Sec) metabolism is crucial for cellular function and ferroptosis prevention
and begins with the uptake of the Sec carrier, selenoprotein P (SELENOP). Following …

Ferroptosis is a cell death modality in which iron-dependent lipid peroxides accumulate on
cell membranes. Cysteine, a limiting substrate for the glutathione system that neutralizes …

Ferroptosis, a regulated cell death hallmarked by unrestrained lipid peroxidation, plays a
pivotal role in the pathophysiology of various diseases, making it a promising therapeutic …

Ferroptosis, driven by an imbalance in redox homeostasis, has recently been identified to
regulate macrophage function and inflammatory responses. SENP3 is a redox-sensitive de …

Ferroptosis is a non-apoptotic mode of programmed cell death characterized by iron
dependence and lipid peroxidation. Since the ferroptosis was proposed, researchers have …

Ferroptosis, a regulated form of cell death, is intricately linked to iron‑dependent lipid
peroxidation. Recent evidence strongly supports the induction of ferroptosis as a promising …

Ferroptosis is a new discovered regulated cell death triggered by the ferrous ion (Fe2+)-
dependent accumulation of lipid peroxides associated with cancer and many other …

Ferroptosis is a pervasive non-apoptotic form of cell death highly relevant in various
degenerative diseases and malignancies. The hallmark of ferroptosis is uncontrolled and …