Pathogenesis and virulence of Candida albicans

JP Lopes, MS Lionakis - Virulence, 2022 - Taylor & Francis
Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …

[HTML][HTML] Invasive candidiasis

PG Pappas, MS Lionakis, MC Arendrup… - Nature Reviews …, 2018 - nature.com
Invasive candidiasis is an important health-care-associated fungal infection that can be
caused by several Candida spp.; the most common species is Candida albicans, but the …

Interactions of fungal pathogens with phagocytes

LP Erwig, NAR Gow - Nature Reviews Microbiology, 2016 - nature.com
The surveillance and elimination of fungal pathogens rely heavily on the sentinel behaviour
of phagocytic cells of the innate immune system, especially macrophages and neutrophils …

The regulatory roles of neutrophils in adaptive immunity

Y Li, W Wang, F Yang, Y Xu, C Feng, Y Zhao - Cell Communication and …, 2019 - Springer
Neutrophils have long been considered as cells playing a crucial role in the immune
defence against invading pathogens. Accumulating evidence strongly supported the direct …

Interleukin-10 and the interleukin-10 receptor

KW Moore, R de Waal Malefyt… - Annual review of …, 2001 - annualreviews.org
Interleukin-10 (IL-10), first recognized for its ability to inhibit activation and effector function of
T cells, monocytes, and macrophages, is a multifunctional cytokine with diverse effects on …

C5a-licensed phagocytes drive sterilizing immunity during systemic fungal infection

JV Desai, D Kumar, T Freiwald, D Chauss… - Cell, 2023 - cell.com
Systemic candidiasis is a common, high-mortality, nosocomial fungal infection.
Unexpectedly, it has emerged as a complication of anti-complement C5-targeted …

Type 1/Type 2 immunity in infectious diseases

B Spellberg, JE Edwards Jr - Clinical Infectious Diseases, 2001 - academic.oup.com
Abstract T helper type 1 (Th1) lymphocytes secrete secrete interleukin (IL)-2, interferon-γ,
and lymphotoxin-α and stimulate type 1 immunity, which is characterized by intense …

[PDF][PDF] The neutrophil as a cellular source of chemokines

S Gasperini, F Calzetti, F Bazzoni, MA Cassatella - Immunol Rev, 2000 - academia.edu
Neutrophils are known to play an important role in inflammatory responses by virtue of their
ability to perform a series of effector functions that collectively represent a major mechanism …

Host control of fungal infections: lessons from basic studies and human cohorts

MS Lionakis, SM Levitz - Annual review of immunology, 2018 - annualreviews.org
In the last few decades, the AIDS pandemic and the significant advances in the medical
management of individuals with neoplastic and inflammatory conditions have resulted in a …

The production of cytokines by polymorphonuclear neutrophils

MA Cassatella - Immunology today, 1995 - cell.com
Cytokines orchestrate the complex netuwrk of cellular interactions that regulate effector cell
functions of natural and immune resistance. Although T cells, natural killer (NK) cells and …