M cells: intelligent engineering of mucosal immune surveillance

A Dillon, DD Lo - Frontiers in immunology, 2019 - frontiersin.org
M cells are specialized intestinal epithelial cells that provide the main machinery for
sampling luminal microbes for mucosal immune surveillance. M cells are usually found in …

Nanoparticle entry into cells; the cell biology weak link

G Griffiths, J Gruenberg, M Marsh, J Wohlmann… - Advanced Drug Delivery …, 2022 - Elsevier
Nanoparticles (NP) are attractive options for the therapeutic delivery of active
pharmaceutical drugs, proteins and nucleic acids into cells, tissues and organs. Research …

Roles for actin assembly in endocytosis

OL Mooren, BJ Galletta… - Annual review of …, 2012 - annualreviews.org
Endocytosis includes a number of processes by which cells internalize segments of their
plasma membrane, enclosing a wide variety of material from outside the cell. Endocytosis …

Ebola virus enters host cells by macropinocytosis and clathrin-mediated endocytosis

P Aleksandrowicz, A Marzi, N Biedenkopf… - The Journal of …, 2011 - academic.oup.com
Virus entry into host cells is the first step of infection and a crucial determinant of
pathogenicity. Here we show that Ebola virus-like particles (EBOV-VLPs) composed of the …

[HTML][HTML] Listeria monocytogenes, a unique model in infection biology: an overview

P Cossart, A Toledo-Arana - Microbes and infection, 2008 - Elsevier
This review rather than covering the whole field intends to highlight recent findings on the
Listeria monocytogenes infectious process or some Listeria specific traits, place them within …

The Pore-Forming Toxin Listeriolysin O Mediates a Novel Entry Pathway of L. monocytogenes into Human Hepatocytes

S Vadia, E Arnett, AC Haghighat… - PLoS …, 2011 - journals.plos.org
Intracellular pathogens have evolved diverse strategies to invade and survive within host
cells. Among the most studied facultative intracellular pathogens, Listeria monocytogenes is …

Nanoparticle accumulation and transcytosis in brain endothelial cell layers

D Ye, MN Raghnaill, M Bramini, E Mahon, C Åberg… - Nanoscale, 2013 - pubs.rsc.org
The blood–brain barrier (BBB) is a selective barrier, which controls and limits access to the
central nervous system (CNS). The selectivity of the BBB relies on specialized …

Rickettsial outer‐membrane protein B (rOmpB) mediates bacterial invasion through Ku70 in an actin, c‐Cbl, clathrin and caveolin 2‐dependent manner

YGY Chan, MM Cardwell, TM Hermanas… - Cellular …, 2009 - Wiley Online Library
Rickettsia conorii, an obligate intracellular tick‐borne pathogen and the causative agent of
Mediterranean spotted fever, binds to and invades non‐phagocytic mammalian cells …

Endocytosis of the anthrax toxin is mediated by clathrin, actin and unconventional adaptors

L Abrami, M Bischofberger, B Kunz, R Groux… - PLoS …, 2010 - journals.plos.org
The anthrax toxin is a tripartite toxin, where the two enzymatic subunits require the third
subunit, the protective antigen (PA), to interact with cells and be escorted to their cytoplasmic …

Frustrated clathrin-mediated endocytosis–causes and possible functions

F Baschieri, K Porshneva… - Journal of cell …, 2020 - journals.biologists.com
Clathrin-mediated endocytosis is the main entry route for most cell surface receptors and
their ligands. It is regulated by clathrin-coated structures that are endowed with the ability to …