Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

G Cirino, C Szabo… - Physiological …, 2023 - journals.physiology.org
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

Reactive Sulfur Species in human diseases

M Iciek, A Bilska-Wilkosz, M Kozdrowicki… - Antioxidants & Redox …, 2023 - liebertpub.com
Significance: Reactive sulfur species (RSS) have been recently recognized as redox
molecules no less important than reactive oxygen species or reactive nitrogen species. They …

Label-Free Quantitative Proteomic Analysis of Nitrogen Starvation in Arabidopsis Root Reveals New Aspects of H2S Signaling by Protein Persulfidation

A Jurado-Flores, LC Romero, C Gotor - Antioxidants, 2021 - mdpi.com
Hydrogen sulfide (H2S)-mediated signaling pathways regulate many physiological and
pathophysiological processes in mammalian and plant systems. The molecular mechanism …

Role of 3-Mercaptopyruvate sulfurtransferase (3-MST) in physiology and disease

SP Rao, P Dobariya, H Bellamkonda, SS More - Antioxidants, 2023 - mdpi.com
3-mercaptopyruvate sulfurtransferase (3-MST) plays the important role of producing
hydrogen sulfide. Conserved from bacteria to Mammalia, this enzyme is localized in …

The Impact of H2S on Obesity-Associated Metabolic Disturbances

F Comas, JM Moreno-Navarrete - Antioxidants, 2021 - mdpi.com
Over the last several decades, hydrogen sulfide (H2S) has gained attention as a new
signaling molecule, with extensive physiological and pathophysiological roles in human …

[HTML][HTML] Role of hydrogen sulfide in the regulation of lipid metabolism: Implications on cardiovascular health

F Lorenzo, P Eugenia, C Vincenzo, T Lara - Life sciences, 2024 - Elsevier
Abstract The World Health Organization (WHO) defines obesity as an urgency for health and
a social emergency. Today around 39% of people is overweight, of these over 13% is …

Proteome dynamics of persulfidation in leaf tissue under light/dark conditions and carbon deprivation

A Jurado-Flores, C Gotor, LC Romero - Antioxidants, 2023 - mdpi.com
Hydrogen sulfide (H2S) acts as a signaling molecule in plants, bacteria, and mammals,
regulating various physiological and pathological processes. The molecular mechanism by …

[HTML][HTML] Inflammatory response to bacterial lipopolysaccharide drives iron accumulation in human adipocytes

N Oliveras-Cañellas, J Latorre… - Biomedicine & …, 2023 - Elsevier
The association among increased inflammation, disrupted iron homeostasis, and adipose
tissue dysfunction in obesity has been widely recognized. However, the specific impact of …

[HTML][HTML] Hydrogen Sulfide Regulates Glucose Uptake in Skeletal Muscles via S-Sulfhydration of AMPK in Muscle Fiber Type-Dependent Way

K Li, M Wang, R Wang, X Wang, H Jiao, J Zhao… - The Journal of …, 2023 - Elsevier
Background The effect of hydrogen sulfide (H 2 S) on glucose homeostasis remains to be
elucidated, especially in the state of insulin resistance. Objectives In the present study, we …

Inhibition of the 3-mercaptopyruvate sulfurtransferase—Hydrogen sulfide system promotes cellular lipid accumulation

G Casili, E Randi, T Panagaki, K Zuhra, M Petrosino… - Geroscience, 2022 - Springer
H2S is generated in the adipose tissue by cystathionine γ-lyase, cystathionine β-synthase,
and 3-mercaptopyruvate sulfurtransferase (3-MST). H2S plays multiple roles in the …