Drug-induced liver injury is an important cause of hepatotoxicity and poses a challenging
clinical problem with respect to both diagnosis and management. Patients susceptible to …

Abstract The 4, 4′-diaminodiphenyl sulfone (DDS), also known as dapsone, is traditionally
used as a potent anti-bacterial agent in clinical management of leprosy. For decades …

Importance Dapsone-induced hypersensitivity syndrome (DHS) is a life-threatening adverse
drug reaction. Based on available epidemiologic studies, HLA genotypes may play an …

Background Pneumocystis jiroveci pneumonia (PJP) is an opportunistic fungal infection that
affects immunocompromised patients. The objective of this study was to describe the …

The development and approval of new antimicrobials capable of being used to treat
infections caused by multidrug-resistant pathogens has not kept pace with the rapid …

Pneumocystis carinii pneumonia (PCP) is a major opportunistic infection that affects patients
with human immunodeficiency virus. Although orally administered dapsone leads to high …

Pneumocystis jirovecii is a fungal pathogen that causes pneumocystis pneumonia, a
disease that mainly affects immunocompromised individuals. This fungus has historically …

Background: Knowledge of effectiveness and safety of the nonbiologic, nonantihistamine
treatments used for chronic urticaria is important as in some cases the principal guideline …

Dapsone, initially synthesized for textile dyeing, gained recognition in the 1930s for its
antibacterial properties, leading to its utilization in dermatology for leprosy and dermatitis …

Objectives: The objective was to characterise and identify potential risk factors for
intolerance to multi-drug leprosy therapy (MDT) which prompted a medication change in a …