Homocysteine–from disease biomarker to disease prevention

AD Smith, H Refsum - Journal of internal medicine, 2021 - Wiley Online Library
We have reviewed the literature and have identified more than 100 diseases or conditions
that are associated with raised concentrations of plasma total homocysteine. The …

Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular …

MJ Sarnak, AS Levey, AC Schoolwerth, J Coresh… - Circulation, 2003 - Am Heart Assoc
Chronic kidney disease1 (CKD) is a worldwide public health problem. In the United States,
there is a rising incidence and prevalence of kidney failure, with poor outcomes and high …

Endothelial dysfunction

DH Endemann, EL Schiffrin - Journal of the American Society of …, 2004 - journals.lww.com
Endothelial dysfunction is characterized by a shift of the actions of the endothelium toward
reduced vasodilation, a proinflammatory state, and prothrombic properties. It is associated …

[HTML][HTML] Reverse epidemiology of cardiovascular risk factors in maintenance dialysis patients

K Kalantar-Zadeh, G Block, MH Humphreys… - Kidney international, 2003 - Elsevier
Reverse epidemiology of cardiovascular risk factors in maintenance dialysis patients.
Conventional risk factors of cardiovascular disease and mortality in the general population …

Facts and recommendations about total homocysteine determinations: an expert opinion

H Refsum, AD Smith, PM Ueland, E Nexo… - Clinical …, 2004 - academic.oup.com
Background: Measurement of plasma total homocysteine has become common as new
methods have been introduced. A wide range of disorders are associated with increased …

Chronic kidney disease as cause of cardiovascular morbidity and mortality

R Vanholder, Z Massy, A Argiles… - Nephrology Dialysis …, 2005 - academic.oup.com
To make an evidence-based evaluation of the relationship between kidney failure and
cardiovascular risk, we reviewed the literature obtained from a PubMed search using pre …

[HTML][HTML] The uremic solutes p-cresol and indoxyl sulfate inhibit endothelial proliferation and wound repair

L Dou, E Bertrand, C Cerini, V Faure, J Sampol… - Kidney international, 2004 - Elsevier
The uremic solutes p-cresol and indoxyl sulfate inhibit endothelial proliferation and wound
repair. Background Cardiovascular diseases are the major causes of mortality in uremic …

Cognitive impairment in chronic kidney disease

M Kurella, GM Chertow, J Luan… - Journal of the American …, 2004 - Wiley Online Library
Objectives: To assess the prevalence of cognitive impairment in persons with chronic kidney
disease (CKD) and its relation to the severity of CKD. Design: Cross‐sectional study. Setting …

Obesity and the risk of cardiovascular and all-cause mortality in chronic kidney disease: a systematic review and meta-analysis

M Ladhani, JC Craig, M Irving… - Nephrology Dialysis …, 2017 - academic.oup.com
Background: Obesity is a risk factor for cardiovascular disease and death in people without
chronic kidney disease (CKD), but the effect of obesity in people with CKD is uncertain …

Pathophysiology of vascular calcification in chronic kidney disease

SM Moe, NX Chen - Circulation research, 2004 - Am Heart Assoc
Patients with chronic kidney disease (CKD) on dialysis have 2-to 5-fold more coronary artery
calcification than age-matched individuals with angiographically proven coronary artery …