Early and late gene changes in MPTP mice model of Parkinson's disease employing cDNA microarray

S Mandel, E Grünblatt, G Maor, MBH Youdim - Neurochemical research, 2002 - Springer
Recently, we reported specific brain gene expression changes in the chronic MPTP model in
the late stage of degeneration, employing cDNA expression array, which indicate a “domino” …

Acute and Long Term Effects of 1‐Methyl‐4‐phenyl‐1, 2, 3, 6‐tetrahydropyridine (MPTP) in Tests of Nociception in Mice

JH Rosland, S Hunskaar, OJ Broch… - Pharmacology & …, 1992 - Wiley Online Library
Acute and long term changes in nociception after administration of 1‐methyl‐4‐phenyl‐1, 2,
3, 6‐tetrahydropyridine (MPTP) 80 mg/kg (four injections of 20 mg/kg given at two hr …

The evolution of nigrostriatal neurochemical changes in the MPTP-treated squirrel monkey

I Irwin, LE DeLanney, LS Forno, KT Finnegan… - Brain research, 1990 - Elsevier
The MPTP-treated monkey has become an important model for the study of Parkinson's
disease. However, studies on the acute evolution of the neurotoxic effects of MPTP in …

Increased midbrain dopaminergic cell activity following 2′ CH3-MPTP-induced dopaminergic cell loss: an in vitro electrophysiological study

GL Bernardini, SG Speciale, DC German - Brain Research, 1990 - Elsevier
Several days after the administration of 1-methyl-4-(2′-methylphenyl)-1, 2, 3, 6-
tetrahydropyridine (2′ CH 3-MPTP) to the BALB/cJ mouse there is a loss of midbrain …

Effects of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydroxypyridine (MPTP) on ganglionic transmission.

KA Alkadhi, YH Hogan - Journal of autonomic pharmacology, 1992 - europepmc.org
1. The neurotoxin 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydroxypyridine (MPTP) caused
blockade of ganglionic transmission as evidenced by a marked decrease of the amplitude of …