[HTML][HTML] Synthetic antimicrobial peptides: Characteristics, design, and potential as alternative molecules to overcome microbial resistance

PG Lima, JTA Oliveira, JL Amaral, CDT Freitas… - Life Sciences, 2021 - Elsevier
Recently, the dramatic emergence of antimicrobial resistance has received attention from
World Health Organization. Synthetic antimicrobial peptides (SAMPs) are considered new …

Plant defensins from a structural perspective

V Kovaleva, I Bukhteeva, OY Kit… - International Journal of …, 2020 - mdpi.com
Plant defensins form a family of proteins with a broad spectrum of protective activities
against fungi, bacteria, and insects. Furthermore, some plant defensins have revealed …

The γ-core motif peptides of plant AMPs as novel antimicrobials for medicine and agriculture

MP Slezina, EA Istomina, TV Korostyleva… - International Journal of …, 2022 - mdpi.com
The γ-core motif is a structural element shared by most host antimicrobial peptides (AMPs),
which is supposed to contribute to their antimicrobial properties. In this review, we …

[HTML][HTML] A new bioinspired peptide on defensin from C. annuum fruits: Antimicrobial activity, mechanisms of action and therapeutical potential

GB Taveira, É de Oliveira Mello, TLBV Simão… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Background Antimicrobial peptides, natural or synthetic, appear as promising molecules for
antimicrobial therapy because of their both broad antimicrobial activity and mechanism of …

Synthetic Oligopeptides Mimicking γ-Core Regions of Cysteine-Rich Peptides of Solanum lycopersicum Possess Antimicrobial Activity against Human and Plant …

MP Slezina, EA Istomina, EV Kulakovskaya… - Current Issues in …, 2021 - mdpi.com
Plant cysteine-rich peptides (CRPs) represent a diverse group of molecules involved in
different aspects of plant physiology. Antimicrobial peptides, which directly suppress the …

Potent Anti-Candida Fraction Isolated from Capsicum chinense Fruits Contains an Antimicrobial Peptide That is Similar to Plant Defensin and is Able to Inhibit the …

MCL Aguieiras, LM Resende, TAM Souza… - Probiotics and …, 2021 - Springer
Antimicrobial peptides (AMPs) are molecules present in several life forms, possess broad-
spectrum of inhibitory activity against pathogenic microorganisms, and are a promising …

Structure, dynamics, and function of PsDef2 defensin from Pinus sylvestris

I Bukhteeva, NI Hrunyk, YM Yusypovych, YI Shalovylo… - Structure, 2022 - cell.com
Plant defensins demonstrate high structural stability at extreme temperatures and pH values
and, in general, are non-toxic to mammalian cells. These properties make them attractive …

Antimicrobial peptides from Capsicum chinense fruits: agronomic alternatives against phytopathogenic fungi

L de Azevedo dos Santos, GB Taveira… - Bioscience …, 2020 - portlandpress.com
In recent years, the antimicrobial activity of peptides isolated from a wide variety of organs
from plant species has been reported. However, a few studies have investigated the …

Novel insights into plant defensin ingestion induced metabolic responses in the polyphagous insect pest Helicoverpa armigera

JA Mulla, VA Tamhane - Scientific Reports, 2023 - nature.com
Lepidopteran insect pest Helicoverpa armigera is one of the most destructive pests of crop
plants and several biotechnological approaches are being developed for its control. Plant …

Synthesis, Structure, and Activity of the Antifungal Plant Defensin PvD1

J Skalska, VM Andrade, GL Cena… - Journal of Medicinal …, 2020 - ACS Publications
Available treatments for invasive fungal infections have limitations, including toxicity and the
emergence of resistant strains. Therefore, there is an urgent need for alternative solutions …