Clinical and molecular aspects of human pegiviruses in the interaction host and infectious agent

M Samadi, V Salimi, MR Haghshenas, SM Miri… - Virology Journal, 2022 - Springer
Abstract Background Human pegivirus 1 (HPgV-1) is a Positive-sense single-stranded RNA
(+ ssRNA) virus, discovered in 1995 as a Flaviviridae member, and the closest human virus …

Advanced material against human (including Covid‐19) and plant viruses: nanoparticles as a feasible strategy

GR Tortella, O Rubilar, MC Diez, J Padrão… - Global …, 2021 - Wiley Online Library
The SARS‐CoV‐2 virus outbreak revealed that these nano‐pathogens have the ability to
rapidly change lives. Undoubtedly, SARS‐CoV‐2 as well as other viruses can cause …

[HTML][HTML] Fusion peptide induced modification of membrane organization and dynamics: Implications in developing fusion inhibitors

S Mishra, MS Panda, H Chakraborty - Chemical Physics Impact, 2023 - Elsevier
An essential step in the entrance of enveloped viruses such as coronaviruses, the human
immunodeficiency virus, and influenza is membrane fusion. A unique class of glycoprotein …

Lipid vesicles loaded with an HIV-1 fusion inhibitor peptide as a potential microbicide

E Sánchez-López, A Paús, I Pérez-Pomeda, A Calpena… - Pharmaceutics, 2020 - mdpi.com
The effective use of fusion inhibitor peptides against cervical and colorectal infections
requires the development of sustained release formulations. In this work we comparatively …

Importance of structure-based studies for the design of a novel HIV-1 inhibitor peptide

MJ Gomara, Y Perez, P Gomez-Gutierrez, C Herrera… - Scientific reports, 2020 - nature.com
Based on the structure of an HIV-1 entry inhibitor peptide two stapled-and a retro-enantio
peptides have been designed to provide novel prevention interventions against HIV …

FDA's stamp of approval: Unveiling peptide breakthroughs in cardiovascular diseases, ACE, HIV, CNS, and beyond

O Al Musaimi - Journal of Peptide Science, 2024 - Wiley Online Library
Peptides exhibit significant specificity and effective interaction with therapeutic targets,
positioning themselves as key players in the global pharmaceutical market. They offer …

Peptide amphiphilic-based supramolecular structures with anti-HIV-1 activity

MJ Gómara, R Pons, C Herrera, P Ziprin… - Bioconjugate …, 2021 - ACS Publications
In a previous work, we defined a novel HIV-1 fusion inhibitor peptide (E1P47) with a broad
spectrum of activity against viruses from different clades, subtypes, and tropisms. With the …

The Design and Optimization of Monomeric Multitarget Peptides for the Treatment of Multifactorial Diseases

T Chen, T Sun, Y Bian, Y Pei, F Feng… - Journal of Medicinal …, 2022 - ACS Publications
Compared with single-target drugs, multitarget drugs may improve the safety and efficacy of
the treatment of multifactorial diseases. However, few multitarget drugs are on the market or …

Exploring Viral Interference Using Peptides: Molecular Determinants of HIV‐1 Inhibition by a Peptide Derived from Human Pegivirus‐1 Envelope Protein E2

R Hoffmann, T Ruegamer, J Schaubächer… - …, 2021 - Wiley Online Library
Co‐infection with the human pegivirus 1 (HPgV‐1) often has a beneficial effect on disease
progression in HIV‐1‐infected individuals. Several HPgV‐1 proteins and peptides, including …

[HTML][HTML] Исследование физико-химических и биологических свойств, пептидного состава пепсинового гидролизата молозива коров

СЛ Тихонов, НВ Тихонова, ИГ Данилова… - … . Серия: Пищевые и …, 2022 - cyberleninka.ru
Пептиды относятся к биологически активным веществам различного спектра действия.
Проведены исследования физико-химических свойств пепсинового гидролизата …