The raison d'être of meiosis is shuffling of genetic information via Mendelian segregation
and, within individual chromosomes, by DNA crossing-over. These outcomes are enabled …

Meiotic recombination involves the formation and repair of programmed DNA double-strand
breaks (DSBs) catalyzed by the conserved Spo11 protein. This review summarizes recent …

INTRODUCTION Protein-protein interactions play critical roles in biology, but the structures
of many eukaryotic protein complexes are unknown, and there are likely many interactions …

In the last two decades, an increasing amount of studies have investigated the use of
components based on carbon-(nano) materials in the engineering of neural interfaces, to …

Meiosis is an essential stage in gamete formation in all sexually reproducing organisms.
Studies of mutations in model organisms and of human haplotype patterns are leading to a …

Meiotic recombination between homologous chromosomes initiates via programmed DNA
double-strand breaks (DSBs), generated by complexes comprising Spo11 transesterase …

Meiotic recombination is essential for fertility in most sexually reproducing species. This
process also creates new combinations of alleles and has important consequences for …

Recombination in meiosis is a fascinating case study for the coordination of chromosomal
duplication, repair, and segregation with each other and with progression through a cell …

The function of histone modifications in initiating and regulating the chromosomal events of
the meiotic prophase remains poorly understood. In Saccharomyces cerevisiae, we …

The maintenance of genome integrity is essential for any organism survival and for the
inheritance of traits to offspring. To the purpose, cells have developed a complex DNA repair …