New insights into the correlations between circulating tumor cells and target organ metastasis
Q Zhan, B Liu, X Situ, Y Luo, T Fu, Y Wang… - … and Targeted Therapy, 2023 - nature.com
Organ-specific metastasis is the primary cause of cancer patient death. The distant
metastasis of tumor cells to specific organs depends on both the intrinsic characteristics of …
metastasis of tumor cells to specific organs depends on both the intrinsic characteristics of …
Micro-magnetofluidic system for rare cell analysis: from principle to translation
Rare cells play essential roles in the initiation and progression of diseases and therefore
their analysis is of great interest. The micro-magnetofluidic system is one of the emerging …
their analysis is of great interest. The micro-magnetofluidic system is one of the emerging …
Polyploid cancer cells reveal signatures of chemotherapy resistance
Therapeutic resistance in cancer significantly contributes to mortality, with many patients
eventually experiencing recurrence after initial treatment responses. Recent studies have …
eventually experiencing recurrence after initial treatment responses. Recent studies have …
Cells in the polyaneuploid cancer cell (PACC) state have increased metastatic potential
Although metastasis is the leading cause of cancer deaths, it is quite rare at the cellular
level. Only a rare subset of cancer cells (~ 1 in 1.5 billion) can complete the entire metastatic …
level. Only a rare subset of cancer cells (~ 1 in 1.5 billion) can complete the entire metastatic …
Cancer-related cells and oncosomes in the liquid biopsy of pancreatic cancer patients undergoing surgery
SN Shishido, E Lin, N Nissen, G Courcoubetis… - npj Precision …, 2024 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) has a five-year survival rate of less than 10%
due to its late diagnosis, rapid metastasis, and chemotherapeutic resistance. For a small …
due to its late diagnosis, rapid metastasis, and chemotherapeutic resistance. For a small …
Investigation of liquid biopsy analytes in peripheral blood of individuals after SARS-CoV-2 infection
E Qi, G Courcoubetis, E Liljegren, E Herrera… - …, 2023 - thelancet.com
Background Post-acute COVID-19 syndrome (PACS) is linked to severe organ damage. The
identification and stratification of at-risk SARS-CoV-2 infected individuals is vital to providing …
identification and stratification of at-risk SARS-CoV-2 infected individuals is vital to providing …
[HTML][HTML] Resolving tumor evolution: a phylogenetic approach
L Li, W Xie, L Zhan, S Wen, X Luo, S Xu, Y Cai… - Journal of the National …, 2024 - Elsevier
The evolutionary dynamics of cancer, characterized by its profound heterogeneity, demand
sophisticated tools for a holistic understanding. This review delves into tumor phylogenetics …
sophisticated tools for a holistic understanding. This review delves into tumor phylogenetics …
Determining the efficacy of ExThera Seraph100 blood filtration in patients diagnosed with pancreatic cancer through the liquid biopsy
SN Shishido, D Suresh, G Courcoubetis, B Ye, E Lin… - BJC reports, 2024 - nature.com
Background Cancer becomes lethal as it spreads from the primary site to the rest of the
body. Circulating tumor cells (CTCs) are biomarkers of disease progression and have been …
body. Circulating tumor cells (CTCs) are biomarkers of disease progression and have been …
[HTML][HTML] Multi-Omic Characterization of Single Cells and Cell-Free Components Detected in the Cerebrospinal Fluid of Patients with Leptomeningeal Disease
SN Shishido, A Marvit, D Pham, T Luo, L Xu, J Mason… - Cancers, 2024 - mdpi.com
Abstract Background/Objectives: Up to 30% of patients with breast cancers will develop
brain or leptomeningeal metastases, and this risk is especially high with HER2-positive …
brain or leptomeningeal metastases, and this risk is especially high with HER2-positive …
Circulation of rare events in the liquid biopsy for early detection of lung mass lesions
Background Lung cancer screening with low‐dose computed tomography (CT) scans
(LDCT) has reduced mortality for patients with high‐risk smoking histories, but it has …
(LDCT) has reduced mortality for patients with high‐risk smoking histories, but it has …