Peroxisomes are unique among the organelles of the endomembrane system. Unlike other
organelles that derive most if not all of their proteins from the ER (endoplasmic reticulum) …

The biogenesis of peroxisomal matrix and membrane proteins is substantially different from
the biogenesis of proteins of other subcellular compartments, such as mitochondria and …

Peroxisomes are vital metabolic organelles that import their lumenal (matrix) enzymes from
the cytosol using mobile receptors. Surprisingly, the receptors can even import folded …

Peroxisomes constitute a dynamic compartment in all nucleated cells. They fulfill diverse
metabolic tasks in response to environmental changes and cellular demands. This …

Isothermal titration calorimetry (ITC) is a fast, accurate and label‐free method for measuring
the thermodynamics and binding affinities of molecular associations in solution. Because the …

The cycling import receptor PEX5 and its membrane-located binding partner PEX14 are key
constituents of the peroxisomal import machinery. Upon recognition of newly synthesized …

Peroxisomes are essential organelles responsible for many metabolic reactions, such as the
oxidation of very long chain and branched fatty acids, D-amino acids and polyamines, as …

The biogenesis of peroxisomes is an ubiquitin-dependent process. In particular, the import
of matrix proteins into the peroxisomal lumen requires the modification of import receptors …

Pichia pastoris (Pp) Pex8p, the only known intraperoxisomal peroxin at steady state, is
targeted to peroxisomes by either the peroxisomal targeting signal (PTS) type 1 or PTS2 …

To facilitate a greater understanding of the biological processes in the medically important
Leishmania donovani parasite, a combination of differential and density-gradient …