Pharmacophore screening, molecular docking, ADMET prediction and MD simulations for identification of ALK and MEK potential dual inhibitors

H Zhang, L Zhang, C Gao, R Yu, C Kang - Journal of Molecular Structure, 2021 - Elsevier
Anaplastic lymphoma kinase (ALK) fusion gene is a common driver gene in non-small cell
lung cancer (NSCLC). The activation of mitogen-activated protein kinase (MAPK) and other …

Rice straw enhancing catalysis of Pseudomonas fluorescens lipase for synthesis of citronellyl acetate

M Yuan, F Cong, Y Zhai, P Li, W Yang, S Zhang… - Bioprocess and …, 2022 - Springer
Citronellyl acetate as an important flavor, can be effectively synthesized by lipase catalysis
in nonaqueous system. But lipases usually behave low catalytic activity due to aggregation …

Copper Phthalocyanine Improving Nonaqueous Catalysis of Pseudomonas cepacia Lipase for Ester Synthesis

X Liu, F Cong, M Han, L Zhang, Z Wang, L Jiang… - Applied Biochemistry …, 2024 - Springer
The nonaqueous catalysis of lipases is significant for synthesis of high pure esters, but they
usually behave low catalytic activity due to denaturation and aggregation of enzyme protein …

Targeting GluR3 in Depression and Alzheimer's Disease: Novel Compounds and Therapeutic Prospects

A Saeed, T Alharazi, K Alshaghdali… - Journal of …, 2024 - content.iospress.com
Background: The present study investigates the interrelated pathophysiology of depression
and Alzheimer's disease (AD), with the objective of elucidating common underlying …

The effect of double (S238F/W159H) mutations on the structure and dynamics of PET degrading enzyme

AR Mhashal, N Kumar T, N Kumar… - Journal of …, 2023 - Taylor & Francis
Polyethylene terephthalate (PET) is one of the highly produced synthetic polymers
worldwide and had acquired attention due to its impact resistance, high clarity, and light …

RETRACTED ARTICLE: Copper Phthalocyanine Improving Nonaqueous Catalysis of Pseudomonas cepacia Lipase for Ester Synthesis

X Liu, F Cong, M Han, L Zhang, Z Wang, L Jiang… - Applied Biochemistry …, 2022 - Springer
The nonaqueous catalysis of lipases is significant for synthesis of high pure esters, but they
usually behave low catalytic activity due to denaturation and aggregation of enzyme protein …