Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades?

M Vallet-Regí, F Schüth, D Lozano, M Colilla… - Chemical Society …, 2022 - pubs.rsc.org
The present review details a chronological description of the events that took place during
the development of mesoporous materials, their different synthetic routes and their use as …

Mesoporous silica and organosilica nanoparticles: physical chemistry, biosafety, delivery strategies, and biomedical applications

JG Croissant, Y Fatieiev, A Almalik… - Advanced healthcare …, 2018 - Wiley Online Library
Predetermining the physico‐chemical properties, biosafety, and stimuli‐responsiveness of
nanomaterials in biological environments is essential for safe and effective biomedical …

Iron oxide@ mesoporous silica Core-Shell nanoparticles as multimodal platforms for magnetic resonance imaging, magnetic hyperthermia, near-infrared light …

A Adam, D Mertz - Nanomaterials, 2023 - mdpi.com
The design of core-shell nanocomposites composed of an iron oxide core and a silica shell
offers promising applications in the nanomedicine field, especially for developing efficient …

Mesoporous silica nanoparticles for the treatment of complex bone diseases: Bone cancer, bone infection and osteoporosis

M Gisbert-Garzarán, M Manzano, M Vallet-Regí - Pharmaceutics, 2020 - mdpi.com
Bone diseases, such as bone cancer, bone infection and osteoporosis, constitute a major
issue for modern societies as a consequence of their progressive ageing. Even though …

siRNA delivery using intelligent chitosan-capped mesoporous silica nanoparticles for overcoming multidrug resistance in malignant carcinoma cells

R Heidari, P Khosravian, SA Mirzaei, F Elahian - Scientific reports, 2021 - nature.com
Although siRNA is a promising technology for cancer gene therapy, effective cytoplasmic
delivery has remained a significant challenge. In this paper, a potent siRNA transfer system …

[HTML][HTML] Recent advances of drug delivery nanocarriers in osteosarcoma treatment

SY Wang, HZ Hu, XC Qing, ZC Zhang… - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
Osteosarcoma is the most common primary malignant bone tumor mainly occurred in
children and adolescence, and chemotherapy is limited for the side effects and development …

Mesoporous silica nanoparticles: Synthesis and multifaceted functionalization for controlled drug delivery

J Gupta, M Quadros, M Momin - Journal of Drug Delivery Science and …, 2023 - Elsevier
Inorganic mesoporous silica nanoparticles (MSN) are porous materials extensively studied
for drug delivery due to their properties such as facile and diverse synthesis methods …

Nanomaterial-mediated autophagy: Coexisting hazard and health benefits in biomedicine

X Feng, Y Zhang, C Zhang, X Lai, Y Zhang… - Particle and fibre …, 2020 - Springer
Background Widespread biomedical applications of nanomaterials (NMs) bring about
increased human exposure risk due to their unique physicochemical properties. Autophagy …

Mesoporous silica nanomaterials: versatile nanocarriers for cancer theranostics and drug and gene delivery

S Kesse, KO Boakye-Yiadom, BO Ochete… - Pharmaceutics, 2019 - mdpi.com
Mesoporous silica nanomaterials (MSNs) have made remarkable achievements and are
being thought of by researchers as materials that can be used to effect great change in …

Highly efficient siRNA delivery from core–shell mesoporous silica nanoparticles with multifunctional polymer caps

K Möller, K Müller, H Engelke, C Bräuchle, E Wagner… - Nanoscale, 2016 - pubs.rsc.org
A new general route for siRNA delivery is presented combining porous core–shell silica
nanocarriers with a modularly designed multifunctional block copolymer. Specifically, the …