Small molecules regulating reactive oxygen species homeostasis for cancer therapy
J Zhang, D Duan, ZL Song, T Liu… - Medicinal Research …, 2021 - Wiley Online Library
Elevated intracellular reactive oxygen species (ROS) and antioxidant defense systems have
been recognized as one of the hallmarks of cancer cells. Compared with normal cells …
been recognized as one of the hallmarks of cancer cells. Compared with normal cells …
Recent developments on other platinum metal complexes as target-specific anticancer therapeutics
TS Prathima, B Choudhury, MG Ahmad… - Coordination Chemistry …, 2023 - Elsevier
Numerous biologically active metal complexes are reported for their unique features and
enhanced functions, particularly towards the inhibition of cancer progression. With the …
enhanced functions, particularly towards the inhibition of cancer progression. With the …
Curcumin–cisplatin chemotherapy: A novel strategy in promoting chemotherapy efficacy and reducing side effects
The efficacy of chemotherapy in cancer therapy is limited due to resistance, treatment
selectivity, and severe adverse effects. Immunotherapy, chemotherapy, targeted therapy …
selectivity, and severe adverse effects. Immunotherapy, chemotherapy, targeted therapy …
[HTML][HTML] Drug uptake-based chemoresistance in breast cancer treatment
H Muley, R Fado, R Rodriguez-Rodriguez… - Biochemical …, 2020 - Elsevier
Breast cancer is the most prevalent type of tumor and the second leading cause of death
due to cancer among women. Although screening methods, diagnosis and therapeutic …
due to cancer among women. Although screening methods, diagnosis and therapeutic …
[HTML][HTML] Green synthesis and anticancer activity of silver nanoparticles prepared using fruit extract of Azadirachta indica
NS Alharbi, NS Alsubhi - Journal of Radiation Research and Applied …, 2022 - Elsevier
Effective cancer therapies with limited side effects are urgently needed, for which silver
nanoparticles (AgNPs) have shown potential. However, environmentally friendly methods for …
nanoparticles (AgNPs) have shown potential. However, environmentally friendly methods for …
Copper complexes as anticancer agents targeting topoisomerases I and II
C Molinaro, A Martoriati, L Pelinski, K Cailliau - Cancers, 2020 - mdpi.com
Simple Summary Organometallics, such as copper compounds, are cancer
chemotherapeutics used alone or in combination with other drugs. One small group of …
chemotherapeutics used alone or in combination with other drugs. One small group of …
Aerosolized niosome formulation containing gemcitabine and cisplatin for lung cancer treatment: Optimization, characterization and in vitro evaluation
NI Mohamad Saimi, N Salim, N Ahmad, E Abdulmalek… - Pharmaceutics, 2021 - mdpi.com
Gemcitabine (Gem) and cisplatin (Cis) are currently being used for lung cancer treatment,
but they are highly toxic in high dosages. This research aimed to develop a niosome …
but they are highly toxic in high dosages. This research aimed to develop a niosome …
Resveratrol protects against cisplatin-induced ovarian and uterine toxicity in female rats by attenuating oxidative stress, inflammation and apoptosis
Cisplatin is an important antineoplastic drug used in multiple chemotherapeutic regimens
but unfortunately causes serious toxic effects as ovarian and uterine toxicity. This study …
but unfortunately causes serious toxic effects as ovarian and uterine toxicity. This study …
The latest advances of cisplatin liposomal formulations: essentials for preparation and analysis
F Zahednezhad, P Zakeri-Milani… - Expert opinion on …, 2020 - Taylor & Francis
Introduction: Cisplatin has been indicated for several malignancies all over the world for
many years. Increasing patient tolerance for high dose of chemotherapeutics and reducing …
many years. Increasing patient tolerance for high dose of chemotherapeutics and reducing …
Fatty acids in cancer chemoresistance
J Qin, L Ye, X Wen, X Zhang, Y Di, Z Chen, Z Wang - Cancer Letters, 2023 - Elsevier
Despite the remarkable clinical success of immunotherapy and molecular targeted therapy
in patients with advanced tumors, chemotherapy remains the most commonly used …
in patients with advanced tumors, chemotherapy remains the most commonly used …