Small molecules regulating reactive oxygen species homeostasis for cancer therapy

J Zhang, D Duan, ZL Song, T Liu… - Medicinal Research …, 2021 - Wiley Online Library
Elevated intracellular reactive oxygen species (ROS) and antioxidant defense systems have
been recognized as one of the hallmarks of cancer cells. Compared with normal cells …

Recent developments on other platinum metal complexes as target-specific anticancer therapeutics

TS Prathima, B Choudhury, MG Ahmad… - Coordination Chemistry …, 2023 - Elsevier
Numerous biologically active metal complexes are reported for their unique features and
enhanced functions, particularly towards the inhibition of cancer progression. With the …

Curcumin–cisplatin chemotherapy: A novel strategy in promoting chemotherapy efficacy and reducing side effects

Y Hussain, L Islam, H Khan, R Filosa… - Phytotherapy …, 2021 - Wiley Online Library
The efficacy of chemotherapy in cancer therapy is limited due to resistance, treatment
selectivity, and severe adverse effects. Immunotherapy, chemotherapy, targeted therapy …

[HTML][HTML] Drug uptake-based chemoresistance in breast cancer treatment

H Muley, R Fado, R Rodriguez-Rodriguez… - Biochemical …, 2020 - Elsevier
Breast cancer is the most prevalent type of tumor and the second leading cause of death
due to cancer among women. Although screening methods, diagnosis and therapeutic …

[HTML][HTML] Green synthesis and anticancer activity of silver nanoparticles prepared using fruit extract of Azadirachta indica

NS Alharbi, NS Alsubhi - Journal of Radiation Research and Applied …, 2022 - Elsevier
Effective cancer therapies with limited side effects are urgently needed, for which silver
nanoparticles (AgNPs) have shown potential. However, environmentally friendly methods for …

Copper complexes as anticancer agents targeting topoisomerases I and II

C Molinaro, A Martoriati, L Pelinski, K Cailliau - Cancers, 2020 - mdpi.com
Simple Summary Organometallics, such as copper compounds, are cancer
chemotherapeutics used alone or in combination with other drugs. One small group of …

Aerosolized niosome formulation containing gemcitabine and cisplatin for lung cancer treatment: Optimization, characterization and in vitro evaluation

NI Mohamad Saimi, N Salim, N Ahmad, E Abdulmalek… - Pharmaceutics, 2021 - mdpi.com
Gemcitabine (Gem) and cisplatin (Cis) are currently being used for lung cancer treatment,
but they are highly toxic in high dosages. This research aimed to develop a niosome …

Resveratrol protects against cisplatin-induced ovarian and uterine toxicity in female rats by attenuating oxidative stress, inflammation and apoptosis

MA Ibrahim, IA Albahlol, FA Wani, AAE Tammam… - Chemico-Biological …, 2021 - Elsevier
Cisplatin is an important antineoplastic drug used in multiple chemotherapeutic regimens
but unfortunately causes serious toxic effects as ovarian and uterine toxicity. This study …

The latest advances of cisplatin liposomal formulations: essentials for preparation and analysis

F Zahednezhad, P Zakeri-Milani… - Expert opinion on …, 2020 - Taylor & Francis
Introduction: Cisplatin has been indicated for several malignancies all over the world for
many years. Increasing patient tolerance for high dose of chemotherapeutics and reducing …

Fatty acids in cancer chemoresistance

J Qin, L Ye, X Wen, X Zhang, Y Di, Z Chen, Z Wang - Cancer Letters, 2023 - Elsevier
Despite the remarkable clinical success of immunotherapy and molecular targeted therapy
in patients with advanced tumors, chemotherapy remains the most commonly used …