Optical coherence tomography (OCT) is a new method that could aid analysis of
neurodegeneration in multiple sclerosis (MS) by capturing thinning of the retinal nerve fibre …

Neuromyelitis optica (NMO) is an inflammatory autoimmune disease of the central nervous
system that preferentially targets the optic nerves and spinal cord. The clinical presentation …

Background Retinal optical coherence tomography (OCT) is an imaging biomarker for
neurodegeneration in multiple sclerosis (MS). In order to become validated as an outcome …

Background Structural retinal imaging biomarkers are important for early recognition and
monitoring of inflammation and neurodegeneration in multiple sclerosis. With the …

Macular oedema typically results from blood–retinal barrier disruption. It has recently been
reported that patients with multiple sclerosis treated with FTY-720 (fingolimod) may exhibit …

Objective: Optical coherence tomography (OCT) noninvasively quantifies retinal nerve fiber
layer (RNFL) thickness. Studies show RNFL thinning in multiple sclerosis (MS), and we …

The onset of multiple sclerosis (MS) in childhood poses diagnostic and therapeutic
challenges, particularly if the symptoms of the first demyelinating event resemble acute …

Many promising MRI approaches for research or clinical management of multiple sclerosis
(MS) have recently emerged, or are under development or refinement. Advanced MRI …

The pathophysiology of multiple sclerosis (MS) is characterized by demyelination, which
culminates in a reduction in axonal transmission. Axonal and neuronal degeneration seem …

Optic neuritis (ON) is an acute inflammatory demyelinating disorder of the optic nerve. The
general characteristics of isolated ON include unilateral, subacute, and painful visual loss …