[HTML][HTML] Obesity and obesity-induced inflammatory disease contribute to atherosclerosis: a review of the pathophysiology and treatment of obesity

RJ Henning - American journal of cardiovascular disease, 2021 - ncbi.nlm.nih.gov
Two billion people worldwide older than 18 years of age, or approximately 30% of the world
population, are overweight or obese. In addition, more than 43 million children under the …

Macrophage polarization in chronic inflammatory diseases: killers or builders?

L Parisi, E Gini, D Baci, M Tremolati… - Journal of …, 2018 - Wiley Online Library
Macrophages are key cellular components of the innate immunity, acting as the main player
in the first‐line defence against the pathogens and modulating homeostatic and …

Human milk oligosaccharides and immune system development

J Plaza-Díaz, L Fontana, A Gil - Nutrients, 2018 - mdpi.com
Maternal milk contains compounds that may affect newborn immunity. Among these are a
group of oligosaccharides that are synthesized in the mammary gland from lactose; these …

Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota

M Serino, E Luche, S Gres, A Baylac, M Bergé… - Gut, 2012 - gut.bmj.com
Objective The gut microbiota, which is considered a causal factor in metabolic diseases as
shown best in animals, is under the dual influence of the host genome and nutritional …

A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent …

MTA Nguyen, S Favelyukis, AK Nguyen… - Journal of biological …, 2007 - ASBMB
Obesity and type 2 diabetes are characterized by decreased insulin sensitivity, elevated
concentrations of free fatty acids (FFAs), and increased macrophage infiltration in adipose …

Environmental obesogens: organotins and endocrine disruption via nuclear receptor signaling

F Grün, B Blumberg - Endocrinology, 2006 - academic.oup.com
Over the last two decades, the incidence of obesity and associated metabolic syndrome
diseases has risen dramatically, becoming a global health crisis. Increased caloric intake …

Fatty liver: a novel component of the metabolic syndrome

A Kotronen, H Yki-Järvinen - Arteriosclerosis, thrombosis, and …, 2008 - Am Heart Assoc
Although the epidemic of obesity has been accompanied by an increase in the prevalence
of the metabolic syndrome, not all obese develop the syndrome and even lean individuals …

Macrophages in human visceral adipose tissue: increased accumulation in obesity and a source of resistin and visfatin

CA Curat, V Wegner, C Sengenes, A Miranville… - Diabetologia, 2006 - Springer
Aims/hypothesis Increased visceral white adipose tissue (WAT) is linked to the risk of
developing diabetes. Methods/results We showed by fluorescence activated cell sorting …

TNF-α and obesity

T Tzanavari, P Giannogonas, KP Karalis - TNF Pathophysiology, 2010 - karger.com
Obesity, an epidemic of our times with rates rising to alarming levels, is associated with
comorbidities including cardiovascular diseases, arthritis, certain cancers, and degenerative …

Mechanisms of disease progression in nonalcoholic fatty liver disease

J Jou, SS Choi, AM Diehl - Seminars in liver disease, 2008 - thieme-connect.com
Nonalcoholic fatty liver disease (NAFLD) encompasses a spectrum of hepatic pathology,
ranging from simple steatosis (also called nonalcoholic fatty liver or NAFL) in its most benign …