Biology of bone tissue: structure, function, and factors that influence bone cells
R Florencio-Silva, GRS Sasso… - BioMed research …, 2015 - Wiley Online Library
Bone tissue is continuously remodeled through the concerted actions of bone cells, which
include bone resorption by osteoclasts and bone formation by osteoblasts, whereas …
include bone resorption by osteoclasts and bone formation by osteoblasts, whereas …
Osteoblast and osteocyte: games without frontiers
The portrait of osteoblasts and osteocytes has been subjected to a revision, since a large
body of evidence is attributing these cells amazing roles both inside and outside the bone …
body of evidence is attributing these cells amazing roles both inside and outside the bone …
Therapeutic strategies targeting connexins
The connexin family of channel-forming proteins is present in every tissue type in the human
anatomy. Connexins are best known for forming clustered intercellular channels, structurally …
anatomy. Connexins are best known for forming clustered intercellular channels, structurally …
Connexins in cardiovascular and neurovascular health and disease: pharmacological implications
Connexins are ubiquitous channel forming proteins that assemble as plasma membrane
hemichannels and as intercellular gap junction channels that directly connect cells. In the …
hemichannels and as intercellular gap junction channels that directly connect cells. In the …
Life cycle of connexins in health and disease
DW Laird - Biochemical Journal, 2006 - portlandpress.com
Evaluation of the human genome suggests that all members of the connexin family of gap-
junction proteins have now been successfully identified. This large and diverse family of …
junction proteins have now been successfully identified. This large and diverse family of …
Connexins in the heart: regulation, function and involvement in cardiac disease
A Rodríguez-Sinovas, JA Sánchez… - International journal of …, 2021 - mdpi.com
Connexins are a family of transmembrane proteins that play a key role in cardiac physiology.
Gap junctional channels put into contact the cytoplasms of connected cardiomyocytes …
Gap junctional channels put into contact the cytoplasms of connected cardiomyocytes …
Bidirectional communication between oocytes and follicle cells: ensuring oocyte developmental competence
GM Kidder, BC Vanderhyden - Canadian journal of physiology …, 2010 - cdnsciencepub.com
Female fertility is determined to a large extent by the quality (developmental competence) of
the oocyte as reflected in its ability to undergo meiosis, be fertilized, and give rise to a …
the oocyte as reflected in its ability to undergo meiosis, be fertilized, and give rise to a …
Implications and challenges of connexin connections to cancer
CC Naus, DW Laird - Nature Reviews Cancer, 2010 - nature.com
The idea that the gap junction family of proteins, connexins, are tumour suppressors has
been widely supported through numerous cancer models. However, the paradigm that …
been widely supported through numerous cancer models. However, the paradigm that …
Ion channels in development and cancer
E Bates - Annual review of cell and developmental biology, 2015 - annualreviews.org
Ion channels have emerged as regulators of developmental processes. In model organisms
and in people with mutations in ion channels, disruption of ion channel function can affect …
and in people with mutations in ion channels, disruption of ion channel function can affect …
Biological role of connexin intercellular channels and hemichannels
R Kar, N Batra, MA Riquelme, JX Jiang - Archives of biochemistry and …, 2012 - Elsevier
Gap junctions (GJ) and hemichannels (HC) formed from the protein subunits called
connexins are transmembrane conduits for the exchange of small molecules and ions …
connexins are transmembrane conduits for the exchange of small molecules and ions …