Epithelial-mesenchymal transition (EMT) refers to a process in which epithelial cells lose
apical-basal polarity and loosen cell–cell junctions to take on mesenchymal cell …

Since its debut in the biomedical research fields in 1981, zebrafish have been used as a
vertebrate model organism in more than 40,000 biomedical research studies. Especially …

The maturation of single-cell transcriptomic technologies has facilitated the generation of
comprehensive cellular atlases from whole embryos,,–. A majority of these data, however …

Contact inhibition of locomotion was discovered by Abercrombie more than 50 years ago
and describes the behaviour of fibroblast cells confronting each other in vitro, where they …

Contact inhibition of locomotion (CIL) is the process through which cells move away from
each other after cell-cell contact, and it contributes to malignant invasion and developmental …

Using a descanned, laser-induced guide star and direct wavefront sensing, we demonstrate
adaptive correction of complex optical aberrations at high numerical aperture (NA) and a 14 …

Neural crest cells are highly multipotent stem cells, but it remains unclear how their fate
restriction to specific fates occurs. The direct fate restriction model hypothesises that …

Collective cell chemotaxis, the directed migration of cell groups along gradients of soluble
chemical cues, underlies various developmental and pathological processes. We use neural …

How action potentials regulate myelination by oligodendrocytes is uncertain. We show that
neuronal activity raises [Ca2+] i in developing oligodendrocytes in vivo and that myelin …

The neural crest is a multipotent stem cell–like population that gives rise to a wide range of
derivatives in the vertebrate embryo including elements of the craniofacial skeleton and …