Background Prediction of radiobiological response is a major challenge in radiotherapy. Of
several radiobiological models, the linear-quadratic (LQ) model has been best validated by …

Purpose To review the radiobiological mechanisms of stereotactic body radiation therapy
stereotactic body radiation therapy (SBRT) and stereotactic radiation surgery (SRS) …

If the α/β ratio is high (eg 10 Gy) for tumour clonogen killing, but low (eg 3 Gy) for late normal
tissue complications, then delivering external beam radiotherapy in a large number (20–30) …

The International Commission on Radiation Units and Measurements - Hans-Georg Menzel,
2012 Skip to main content Scheduled maintenance on Monday, November 20th, with …

As soon as relatively accurate dosimetry became available around 1910, it became clear
that the biological effect of a given physical dose of ionizing radiation depends on how this …

We explore the relationship among experimental design, parameter estimation, and
systematic error in sloppy models. We show that the approximate nature of mathematical …

Brain metastases (BMs) frequently occur in primary tumors such as lung cancer, breast
cancer, and melanoma, and are associated with notably short natural survival. In addition to …

Purpose To investigate how necroptosis (ie, programmed necrosis) is involved in killing of
non-small cell lung cancer (NSCLC) after ablative hypofractionated radiation therapy …

This book explores outcome modeling in cancer from a data-centric perspective to enable a
better understanding of complex treatment response, to guide the design of advanced …

Different radiobiological models have been proposed to estimate the cell-killing effects,
which are very important in radiotherapy and radiation risk assessment. However, most …