Update on recent advances in amyotrophic lateral sclerosis
In the last few years, our understanding of disease molecular mechanisms underpinning
ALS has advanced greatly, allowing the first steps in translating into clinical practice novel …
ALS has advanced greatly, allowing the first steps in translating into clinical practice novel …
Upper limb movements as digital biomarkers in people with ALS
Background Objective evaluation of people with amyotrophic lateral sclerosis (PALS) in free-
living settings is challenging. The introduction of portable digital devices, such as wearables …
living settings is challenging. The introduction of portable digital devices, such as wearables …
Portable fixed dynamometry enables home-based, reliable assessment of muscle strength in patients with amyotrophic lateral sclerosis: a pilot study
JWJ Van Unnik, JNE Bakers, S Kokx… - … Lateral Sclerosis and …, 2023 - Taylor & Francis
Objective To determine the feasibility, reliability, and sensitivity of remotely monitoring
muscle strength loss of knee extensors using a novel portable fixed dynamometer (PFD) in …
muscle strength loss of knee extensors using a novel portable fixed dynamometer (PFD) in …
Remote monitoring of amyotrophic lateral sclerosis using wearable sensors detects differences in disease progression and survival: a prospective cohort study
JWJ van Unnik, M Meyjes, MRJ van Mantgem… - Ebiomedicine, 2024 - thelancet.com
Background There is an urgent need for objective and sensitive measures to quantify clinical
disease progression and gauge the response to treatment in clinical trials for amyotrophic …
disease progression and gauge the response to treatment in clinical trials for amyotrophic …
Exploratory study to evaluate the acceptability of a wearable accelerometer to assess motor progression in motor neuron disease
E Beswick, A Christides, A Symonds, M Johnson… - Journal of …, 2024 - Springer
Motor neuron disease (MND) is a rapidly progressive condition traditionally assessed using
a questionnaire to evaluate physical function, the revised amyotrophic lateral sclerosis …
a questionnaire to evaluate physical function, the revised amyotrophic lateral sclerosis …
[PDF][PDF] The use of digital devices to monitor physical behaviour in motor neuron disease: a systematic
LS Musson, N Mitic, V Leigh-Valero… - s3.ca-central-1.amazonaws.com
Background: Motor neuron disease (MND) is a progressive and incurable
neurodegenerative disease. There is an urgent need for sensitive measures of disease …
neurodegenerative disease. There is an urgent need for sensitive measures of disease …