[HTML][HTML] Integrated neurophotonics: toward dense volumetric interrogation of brain circuit activity—at depth and in real time

LC Moreaux, D Yatsenko, WD Sacher, J Choi, C Lee… - Neuron, 2020 - cell.com
We propose a new paradigm for dense functional imaging of brain activity to surmount the
limitations of present methodologies. We term this approach" integrated neurophotonics"; it …

Toward implantable devices for angle-sensitive, lens-less, multifluorescent, single-photon lifetime imaging in the brain using Fabry–Perot and absorptive color filters

AJ Taal, C Lee, J Choi, B Hellenkamp… - Light: Science & …, 2022 - nature.com
Implantable image sensors have the potential to revolutionize neuroscience. Due to their
small form factor requirements; however, conventional filters and optics cannot be …

A Mechanically Flexible, Implantable Neural Interface for Computational Imaging and Optogenetic Stimulation Over 5.4×5.4mm2 FoV

S Moazeni, EH Pollmann… - … Circuits and Systems, 2021 - ieeexplore.ieee.org
Emerging optical functional imaging and optogenetics are among the most promising
approaches in neuroscience to study neuronal circuits. Combining both methods into a …

A 512-pixel, 51-kHz-frame-rate, dual-shank, lens-less, filter-less single-photon avalanche diode CMOS neural imaging probe

J Choi, AJ Taal, EH Pollmann, C Lee… - IEEE journal of solid …, 2019 - ieeexplore.ieee.org
We present an implantable single-photon shank-based imager, monolithically integrated
onto a single CMOS IC. The imager comprises of 512 single-photon avalanche diodes …

Hybrid electrical and optical neural interfaces

Z Ramezani, KJ Seo, H Fang - Journal of Micromechanics and …, 2021 - iopscience.iop.org
Neural interfaces bridge the nervous system and the outside world by recording and
stimulating neurons. Combining electrical and optical modalities in a single, hybrid neural …

Fully integrated time-gated 3D fluorescence imager for deep neural imaging

J Choi, AJ Taal, WL Meng, EH Pollmann… - IEEE transactions on …, 2020 - ieeexplore.ieee.org
This paper presents a device for time-gated fluorescence imaging in the deep brain,
consisting of two on-chip laser diodes and 512 single-photon avalanche diodes (SPADs) …

[图书][B] Implantable Optoelectronics for Neural Interfaces

EH Pollmann - 2023 - search.proquest.com
In neuroscience, optical techniques have become the leading method over
electrophysiological techniques because of their ability to target defined populations upon …

[图书][B] Integration of neural optical recording and stimulation on minimally invasive, deep-brain implantable CMOS

AJ Taal - 2022 - search.proquest.com
This thesis describes the development of a minimally invasive integrated platform for all-
optical neural stimulation and measurement (OptoSAM). The OptoSAM platform is a single …

The Integrated Neurophotonics Paradigm

ML Roukes - CLEO: Applications and Technology, 2022 - opg.optica.org
The Integrated Neurophotonics Paradigm Page 1 The Integrated Neurophotonics Paradigm
Michael L. Roukes Departments of Physics, Applied Physics, and Bioengineering California …

[PDF][PDF] ISSCC 2021/SESSION 19/OPTICAL SYSTEMS FOR EMERGING APPLICATIONS/19.2

S Moazeni, EH Pollmann, V Boominathan, FA Cardoso… - bioee.ee.columbia.edu
The advent of genetically encoded voltage and calcium indicators and optogenetic probes
has unlocked unprecedented capabilities, including near-single-action-potential recording …