Neuroepigenetics of ageing and neurodegeneration-associated dementia: an updated review
Gene expression is tremendously altered in the brain during memory acquisition, recall, and
forgetfulness. However, non-genetic factors, including environmental elements, epigenetic …
forgetfulness. However, non-genetic factors, including environmental elements, epigenetic …
Pathophysiological basis and promise of experimental therapies for Gulf War Illness, a chronic neuropsychiatric syndrome in veterans
This article describes the pathophysiology and potential treatments for Gulf War Illness
(GWI), which is a chronic neuropsychiatric illness linked to a combination of chemical …
(GWI), which is a chronic neuropsychiatric illness linked to a combination of chemical …
[HTML][HTML] Oral nano-curcumin in a model of chronic Gulf War illness alleviates brain dysfunction with modulation of oxidative stress, mitochondrial function …
Unrelenting cognitive and mood impairments concomitant with incessant oxidative stress
and neuroinflammation are among the significant symptoms of chronic Gulf War Illness …
and neuroinflammation are among the significant symptoms of chronic Gulf War Illness …
Ketamine Produces Antidepressant Effects by Inhibiting Histone Deacetylases and Upregulating Hippocampal Brain-Derived Neurotrophic Factor Levels in a …
A Ribeiro-Davis, DY Al Saeedy, FM Jahr… - … of Pharmacology and …, 2024 - ASPET
Approximately one-third of Gulf War veterans suffer from Gulf War Illness (GWI), which
encompasses mood disorders and depressive symptoms. Deployment-related exposure to …
encompasses mood disorders and depressive symptoms. Deployment-related exposure to …
[HTML][HTML] Brain-specific increase in leukotriene signaling accompanies chronic neuroinflammation and cognitive impairment in a model of Gulf war illness
Persistent cognitive impairment is a primary central nervous system-related symptom in
veterans afflicted with chronic Gulf War Illness (GWI). Previous studies in a rat model have …
veterans afflicted with chronic Gulf War Illness (GWI). Previous studies in a rat model have …
Mitigating neuroinflammation in Parkinson's disease: Exploring the role of proinflammatory cytokines and the potential of phytochemicals as natural therapeutics
Parkinson's disease (PD) is one of the most prevalent neuroinflammatory illnesses,
characterized by the progressive loss of neurons in the brain. Proinflammatory cytokines …
characterized by the progressive loss of neurons in the brain. Proinflammatory cytokines …
Repeated exposure to chlorpyrifos is associated with a dose-dependent chronic neurobehavioral deficit in adult rats
ACR Ribeiro, E Hawkins, FM Jahr, JL McClay… - Neurotoxicology, 2022 - Elsevier
Organophosphate (OP) chemicals include commonly used pesticides and chemical warfare
agents, and mechanistically they are potent inhibitors of the cholinesterase (ChE) enzyme …
agents, and mechanistically they are potent inhibitors of the cholinesterase (ChE) enzyme …
Hormonal changes in veterans with Gulf War Illness
Abstract Aims Gulf War Illness (GWI) is a multi-system condition of complex etiology and
pathophysiology without specific treatment. There is an overlap between the symptoms of …
pathophysiology without specific treatment. There is an overlap between the symptoms of …
Epigenetic modification of histone acetylation in the sensorimotor cortex after intracerebral hemorrhage
T Nishio, T Inoue, Y Takamatsu, T Mishima… - Biomedical …, 2024 - jstage.jst.go.jp
Epigenetic regulation is involved in post-stroke neuroplasticity. We investigated the effects of
intracerebral hemorrhage (ICH) on histone acetylation and gene expression related to …
intracerebral hemorrhage (ICH) on histone acetylation and gene expression related to …
Organophospate-Induced Pathology: Mechanisms of Development, Principles of Therapy and Features of Experimental Studies
NV Goncharov, DA Belinskaia, PV Avdonin - Journal of Evolutionary …, 2023 - Springer
Organophosphates (OP) are one of the most common neurotoxic xenobiotics. In acute OP
poisoning, as a result of suppression of synaptic acetylcholinesterase (AChE) activity, a …
poisoning, as a result of suppression of synaptic acetylcholinesterase (AChE) activity, a …