Abstract Type 2 diabetes (T2DM) is a persistent metabolic disorder rising rapidly worldwide.
It is characterized by pancreatic insulin resistance and β-cell dysfunction. Hyperglycemia …

Hypertension and type 2 diabetes are common comorbidities. Hypertension is twice as
frequent in patients with diabetes compared with those who do not have diabetes. Moreover …

Epidemiological studies have suggested that cumulative diabetic exposure, namely
prolonged exposure to chronic hyperglycemia, contributes to the increased risk of …

Wound healing is a well-tuned biological process, which is achieved via consecutive and
overlapping phases including hemostasis, inflammatory-related events, cell proliferation and …

The receptor for advanced glycation end products (RAGE) is a non-specific multi-ligand
pattern recognition receptor capable of binding to a range of structurally diverse ligands …

Alzheimer's disease (AD) is a neurodegenerative disease with amyloid beta (Aβ) deposition
and intracellular neurofibrillary tangles (NFTs) as its characteristic pathological changes …

Cornus officinalis Sieb. et Zucc.(Shanzhuyu), a herb and food plant in east Asia, has the
properties of tonifying the liver and kidney, and nourishing the essence according to the …

Diabetic nephropathy (DN) is a common microvascular complication of diabetes mellitus
(DM), which can lead to renal failure in diabetic patients. At present, the first-line drugs for …

Background Traditional Chinese medicine (TCM) formulations have proven to be
advantageous in clinical treatment and prevention of disease. LiuWei DiHuang Pill (LWDH …

Diabetic mellitus (DM) is a significant public health concern worldwide with an increased
incidence of morbidity and mortality, which is particularly due to the diabetic vascular …