Para-inflammation is a tissue adaptive response to noxious stress or malfunction and has
characteristics that are intermediate between basal and inflammatory states (Medzhitov …

Retinal endothelial cells line the arborizing microvasculature that supplies and drains the
neural retina. The anatomical and physiological characteristics of these endothelial cells are …

Glaucoma is an optic neuropathy in which retinal ganglion cells die probably through an
apoptotic process. Apoptosis is known to involve free radicals in several systems including …

Recent evidence supports the notion that tissue OX2 (CD200) constitutively provides down-
regulatory signals to myeloid-lineage cells via CD200-receptor (CD200R). Thus, mice …

The pleiotropic cytokine tumour necrosis factor-alpha (TNF-α) is released from cells that
include macrophages and T-cells during inflammatory responses, orchestrating the initiation …

Uveitis is an inflammation of the iris, ciliary body, vitreous, retina, or choroid, which has been
shown to be the first manifestation of numerous systemic diseases. Studies about the …

Folic acid (FA), also termed folate, is an essential vitamin for health at all ages since it
participates in the biosynthesis of nucleotides, amino acids, neurotransmitters, and certain …

Experimental autoimmune uveoretinitis (EAU) is an animal model for human intraocular
inflammatory disease. EAU is induced in B10. RIII mice by immunization with RBP-3 161 …

Although the testis is an immunoprivileged organ, infection and inflammation may
overwhelm immunosuppressor mechanisms inducing autoimmune reactions against …

BACKGROUND Experimental autoimmune orchitis (EAO) is a model of chronic inflammation
and infertility useful for studying testicular immune and germ cell (GC) interactions. In this …