[HTML][HTML] Pathobiochemistry of Aging and Neurodegeneration: Deregulation of NAD+ Metabolism in Brain Cells
NA Kolotyeva, AA Groshkov, NA Rozanova… - Biomolecules, 2024 - mdpi.com
NAD+ plays a pivotal role in energy metabolism and adaptation to external stimuli and
stressful conditions. A significant reduction in intracellular NAD+ levels is associated with …
stressful conditions. A significant reduction in intracellular NAD+ levels is associated with …
Adolescent girls with type 1 diabetes develop changes in bone prior to evidence of clinical neuropathy
I Shen, RL Usala, M Mohseni… - The Journal of …, 2024 - academic.oup.com
Context Neuropathy and fracture are prevalent complications of type 1 diabetes (T1D).
Although correlated in the clinical literature, it remains unknown whether neuropathy …
Although correlated in the clinical literature, it remains unknown whether neuropathy …
Central activation of catecholamine-independent lipolysis drives the end-stage catabolism of all adipose tissues
X Zhang, A Majumdar, C Kim, B Kleiboeker… - …, 2024 - pmc.ncbi.nlm.nih.gov
Several adipose depots, including constitutive bone marrow adipose tissue (cBMAT), resist
conventional lipolytic cues, making them metabolically non-responsive. However, under …
conventional lipolytic cues, making them metabolically non-responsive. However, under …
Spatial histomorphometry reveals that local peripheral nerves modulate but are not required for skeletal adaptation to applied load in mice
Mechanical loading is required for bone health and results in skeletal adaptation to optimize
strength. Local nerve axons, particularly within the periosteum, may respond to load-induced …
strength. Local nerve axons, particularly within the periosteum, may respond to load-induced …
Origin, Regulation, and Function of Bone Marrow Adipose Tissue and Implications for Bone Health
X Zhang - 2024 - search.proquest.com
Bone marrow adipose tissue (BMAT) is a unique fat depot located within the skeletal system
that takes up a large portion of the total bone marrow volume and contains tremendous …
that takes up a large portion of the total bone marrow volume and contains tremendous …