The effects of phytochemicals on circadian rhythm and related diseases

T Xu, B Lu - Critical Reviews in Food Science and Nutrition, 2019 - Taylor & Francis
A circadian rhythm is any biological activity rhythm driven by internal circadian clocks (∼ 24
h) and entrained by external signals. Its disruption leads to the development of many …

Cosmeceutical therapy: engaging the repercussions of UVR photoaging on the skin's circadian rhythm

CK Mahendra, HL Ser, P Pusparajah, TT Htar… - International Journal of …, 2022 - mdpi.com
Sunlight is an important factor in regulating the central circadian rhythm, including the
modulation of our sleep/wake cycles. Sunlight had also been discovered to have a …

Epigenetic regulation of the circadian clock: role of 5-aza-2′-deoxycytidine

T Tomita, R Kurita, Y Onishi - Bioscience Reports, 2017 - portlandpress.com
We have been investigating transcriptional regulation of the BMAL1 gene, a critical
component of the mammalian clock system including DNA methylation. Here, a more …

Screening of cytotoxicity and DNA topoisomerase IIa inhibitory activity of Turkish Onosma species

Ö Güzel, S Duman, S Yilmaz… - Turkish Journal of …, 2021 - journals.tubitak.gov.tr
Onosma L., the largest genus of Boraginaceae, is represented by 105 species in Turkey with
an endemism rate of 52%. Phytochemical studies indicate that Boraginaceae plants mainly …

Oncogenic and circadian effects of small molecules directly and indirectly targeting the core circadian clock

HH Lin, KL Robertson, HA Bisbee… - Integrative Cancer …, 2020 - journals.sagepub.com
Circadian rhythms are essential for controlling the cell cycle, cellular proliferation, and
apoptosis, and hence are tightly linked to cell fate. Several recent studies have used small …

Effects of Estrus Cycle on Expression of Ovarian Biological Clock-related Genes of Xiang Pig.

T Liangting, S HUANG, NIU Xi… - … & Technology (1008 …, 2023 - search.ebscohost.com
The biological clock plays a critical role in the reproductive system of various living
organisms like swine. To examine the effects of estrus cycle on the expression of ovarian …

Characterization of the binding of shikonin to human immunoglobulin using scanning electron microscope, molecular modeling and multi-spectroscopic methods

W He, X Ye, X Yao, X Wu, Q Lin, G Huang… - … Acta Part A: Molecular …, 2015 - Elsevier
Shikonin, one of the active components isolated from the root of Arnebia euchroma (Royle)
Johnst, have anti-tumor, anti-bacterial and anti-inflammatory activities and has been used …

The effects of naphthoquinones isolated from Onosma species on DNA topoisomerases and their cytotoxic properties

Ö Güzel - 2018 - search.proquest.com
Onosma L. genus (Boraginaceae) comprises of 230 species that is represented by 102
species and 108 taxa in the flora of Turkey. As 50% of the genus is endemic, Anatolia can be …

The effects of estrus cycle on the expression of ovarian biological clock-related genes of Xiang pigs

LT Tang, S Huang, X Niu, S Li, J Wang, XQ Ran - 2023 - researchsquare.com
The biological clock has been studied to play a critical role in the reproductive system of
various living organisms like swine. To examine the effects of estrus cycle on the expression …

Epigenetic Modulation of Circadian Rhythms: Bmal1 Gene Regulation

T Tomita, Y Onishi - Chromatin and Epigenetics, 2018 - books.google.com
Circadian rhythms that function in behaviour and physiology have adaptive significance for
living organisms from bacteria to humans and reflect the presence of a biological clock. The …