Infections arising from multidrug-resistant pathogenic bacteria are spreading rapidly
throughout the world and threaten to become untreatable. The origins of resistance are …

The peptidoglycan (PG) cell wall is an extra-cytoplasmic glycopeptide polymeric structure
that protects bacteria from osmotic lysis and determines cellular shape. Since the cell wall …

Simple Summary Multidrug-resistant bacterial infections, especially that caused by Gram-
negative bacteria, have posed serious health issues worldwide. Bacteria have different …

Cyclomodulins are bacterial toxins that interfere with the eukaryotic cell cycle. A new
cyclomodulin called colibactin, which is synthetized by the pks genomic island, was …

Antibiotics are being less effective, which leads to high mortality in patients with infections
and a high cost for the recovery of health, and the projections that are had for the future are …

Colibactins are hybrid polyketide-nonribosomal peptides produced by Escherichia coli,
Klebsiella pneumoniae, and other Enterobacteriaceae harboring the pks genomic island …

The emergency of antibiotic-resistant bacteria in severe infections is increasing, especially
in nosocomial environments. The ESKAPE group is of special importance in the groups of …

Although Escherichia coli Nissle 1917 (EcN) has been used therapeutically for over a
century, the determinants of its probiotic properties remain elusive. EcN produces two …

To the multiple factors that may eventually result in colorectal cancer (CRC), strains of E. coli
have now been added, in particular strains producing colibactin from their polyketide …

Microbiota can significantly contribute to colorectal cancer initiation and development. It was
described that E. coli harbouring polyketide synthase (pks) genes can synthetize bacterial …