Multi-omics data integration, interpretation, and its application
I Subramanian, S Verma, S Kumar… - … and biology insights, 2020 - journals.sagepub.com
To study complex biological processes holistically, it is imperative to take an integrative
approach that combines multi-omics data to highlight the interrelationships of the involved …
approach that combines multi-omics data to highlight the interrelationships of the involved …
[HTML][HTML] Methodological and quality flaws in the use of artificial intelligence in mental health research: systematic review
R Tornero-Costa, A Martinez-Millana… - JMIR Mental …, 2023 - mental.jmir.org
Background: Artificial intelligence (AI) is giving rise to a revolution in medicine and health
care. Mental health conditions are highly prevalent in many countries, and the COVID-19 …
care. Mental health conditions are highly prevalent in many countries, and the COVID-19 …
Global evolution of research in artificial intelligence in health and medicine: a bibliometric study
The increasing application of Artificial Intelligence (AI) in health and medicine has attracted
a great deal of research interest in recent decades. This study aims to provide a global and …
a great deal of research interest in recent decades. This study aims to provide a global and …
Dealing with dimensionality: the application of machine learning to multi-omics data
D Feldner-Busztin, P Firbas Nisantzis… - …, 2023 - academic.oup.com
Motivation Machine learning (ML) methods are motivated by the need to automate
information extraction from large datasets in order to support human users in data-driven …
information extraction from large datasets in order to support human users in data-driven …
Metabolomics and multi-omics integration: a survey of computational methods and resources
As researchers are increasingly able to collect data on a large scale from multiple clinical
and omics modalities, multi-omics integration is becoming a critical component of …
and omics modalities, multi-omics integration is becoming a critical component of …
Multi-omics data integration methods and their applications in psychiatric disorders
To study mental illness and health, in the past researchers have often broken down their
complexity into individual subsystems (eg, genomics, transcriptomics, proteomics, clinical …
complexity into individual subsystems (eg, genomics, transcriptomics, proteomics, clinical …
Pharmacometabonomics: data processing and statistical analysis
J Fu, Y Zhang, J Liu, X Lian, J Tang… - Briefings in …, 2021 - academic.oup.com
Individual variations in drug efficacy, side effects and adverse drug reactions are still
challenging that cannot be ignored in drug research and development. The aim of …
challenging that cannot be ignored in drug research and development. The aim of …
Challenges and future prospects of precision medicine in psychiatry
M Manchia, C Pisanu, A Squassina… - Pharmacogenomics …, 2020 - Taylor & Francis
Precision medicine is increasingly recognized as a promising approach to improve disease
treatment, taking into consideration the individual clinical and biological characteristics …
treatment, taking into consideration the individual clinical and biological characteristics …
Exploring the role of gut microbiota in major depressive disorder and in treatment resistance to antidepressants
A Fontana, M Manchia, C Panebianco, P Paribello… - Biomedicines, 2020 - mdpi.com
Major depressive disorder (MDD) is a common severe psychiatric illness, exhibiting sub-
optimal response to existing pharmacological treatments. Although its etiopathogenesis is …
optimal response to existing pharmacological treatments. Although its etiopathogenesis is …
Multi-omics driven predictions of response to acute phase combination antidepressant therapy: a machine learning approach with cross-trial replication
JB Joyce, CW Grant, D Liu… - Translational …, 2021 - nature.com
Combination antidepressant pharmacotherapies are frequently used to treat major
depressive disorder (MDD). However, there is no evidence that machine learning …
depressive disorder (MDD). However, there is no evidence that machine learning …