Skeletal muscle is one of the most dynamic and plastic tissues of the human body. In
humans, skeletal muscle comprises approximately 40% of total body weight and contains 50 …

An eccentric contraction involves the active lengthening of muscle under an external load.
The molecular and neural mechanisms underpinning eccentric contractions differ from those …

This series of reviews focuses on the most important neuromuscular function in many sport
performances, the ability to generate maximal muscular power. Part 1 focuses on the factors …

Whereas a variety of pre-exercise activities have been incorporated as part of a “warm-up”
prior to work, combat, and athletic activities for millennia, the inclusion of static stretching …

The thin and thick filaments of muscle sarcomeres are interconnected by the giant protein
titin, which is a scaffolding filament, signaling platform, and provider of passive tension and …

Titin is a filamentous protein spanning the half-sarcomere, with spring-like properties in the I-
band region. Various structural, signaling, and mechanical functions have been associated …

Recent studies have demonstrated a role for the elastic protein titin in active muscle, but the
mechanisms by which titin plays this role remain to be elucidated. In active muscle, Ca2+ …

This nonexhaustive mini-review reports on the application of eccentric exercise in various
rehabilitation populations. The two defining properties of eccentric muscle contractions—a …

In contrast to isometric and shortening contractions, many observations made on actively
lengthening muscles cannot be readily explained with the sliding filament and cross-bridge …

When active muscles are stretched, our understanding of muscle function is stretched as
well. Our understanding of the molecular mechanisms of concentric contraction has …