Cardiac cell therapy holds a real promise for improving heart function and especially of the
chronically failing myocardium. Embedding cells into 3D biodegradable scaffolds may better …

As a type of elastomeric polymers, non-degradable polyurethanes (PUs) have a long history
of being used in clinics, whereas biodegradable PUs have been developed in recent …

Fabrication of anisotropic materials is highly desirable in designing biomaterials and tissue-
engineered constructs. Electrospinning has been broadly adopted due to its versatility in …

Electrospinning is a simple and affordable method of producing nanofibers, offering a large
specific surface area and highly porous structures with diameters ranging from nanometers …

Fluorescent reporters of cardiac electrophysiology provide valuable information on heart cell
and tissue function. However, motion artifacts caused by cardiac muscle contraction interfere …

Extracellular matrix (ECM) structure and biochemistry provide cell-instructive cues that
promote and regulate tissue growth, function, and repair. From a structural perspective, the …

Tissue engineered scaffolds have emerged as a promising solution for heart valve
replacement because of their potential for regeneration. However, traditional heart valve …

The constant growth of the population has pushed researchers to find novel protein sources.
A possible solution to this problem has been found in cellular agriculture, specifically in the …

In this study, a composite scaffold consisting of an electrospun polyurethane and poly
(ethylene glycol) hydrogel was investigated for aortic valve tissue engineering. This …

Valvular heart diseases are the third leading cause of cardiovascular disease, resulting in
more than 25,000 deaths annually in the United States. Heart valve tissue engineering …