Ulcerative colitis, an immune-mediated inflammatory disease of the gastrointestinal tract,
places a significant financial burden on patients and the healthcare system. Recently …

The dynamic interplay between the immunome and microbiome in reproductive health is a
complex and rapidly advancing research field, holding tremendously vast possibilities for the …

Background Elevated systemic antibody responses against gut microbiota flagellins are
observed in both Crohn's disease (CD) and myalgic encephalomyelitis/chronic fatigue …

Autoantibody binding has a central role in autoimmune diseases and has also been linked
to cancer, infections, and behavioral disorders. Autoimmune neurological diseases remain …

Adaptive immune cell function is regulated by a highly diverse receptor recombined from
variable germline-encoded segments that can recognize an almost unlimited array of …

Characterizing the antibody reactome for circulating antibodies provide insight into
pathogen exposure, allergies and autoimmune diseases. This is important for biomarker …

Encounters with pathogens and other molecules can imprint long-lasting effects on our
immune system, influencing future physiological outcomes. Given the wide range of …

Objective Interstitial lung diseases (ILDs) are a heterogeneous group of disorders that can
develop in patients with connective tissue diseases. Establishing autoimmunity in ILD …

Background and Aims Inflammatory bowel disease is a chronic manifestation of
dysregulated immune response to the gut microbiota in genetically pre-disposed hosts …

There is agreement that inflammatory bowel diseases are, both in terms of species
composition and function, associated with an altered intestinal microbiome. This is usually …