Phytochemistry, pharmacology, and therapeutic uses of black seed (Nigella sativa)

W Kooti, Z Hasanzadeh-Noohi, N Sharafi-Ahvazi… - Chinese journal of …, 2016 - Elsevier
Black seed (Nigella sativa) is an annual flowering plant from Ranunculaceae family, native
to southwest Asia. This plant has many food and medicinal uses. The use of its seeds and oil …

Polo-like kinase 1 inhibitors in human cancer therapy: development and therapeutic potential

J Zhang, L Zhang, J Wang, L Ouyang… - Journal of medicinal …, 2022 - ACS Publications
Polo-like kinase 1 (PLK1) plays an important role in a variety of cellular functions, including
the regulation of mitosis, DNA replication, autophagy, and the epithelial–mesenchymal …

Cumin (Cuminum cyminum) and black cumin (Nigella sativa) seeds: traditional uses, chemical constituents, and nutraceutical effects

K Srinivasan - Food quality and safety, 2018 - academic.oup.com
Although the seeds of cumin (Cuminum cyminum L.) are widely used as a spice for their
distinctive aroma, they are also commonly used in traditional medicine to treat a variety of …

Effective medicinal plant in cancer treatment, part 2: review study

W Kooti, K Servatyari, M Behzadifar… - Journal of evidence …, 2017 - journals.sagepub.com
Cancer is the second cause of death after cardiovascular diseases. With due attention to
rapid progress in the phytochemical study of plants, they are becoming popular because of …

Herbal medicine: biomolecular and clinical aspects

IFF Benzie, S Wachtel-Galor - 2011 - books.google.com
Responding to the increased popularity of herbal medicines and other forms of
complementary or alternative medicine world-wide, this reference reviews and evaluates …

Current advances of nitric oxide in cancer and anticancer therapeutics

J Mintz, A Vedenko, O Rosete, K Shah, G Goldstein… - Vaccines, 2021 - mdpi.com
Nitric oxide (NO) is a short-lived, ubiquitous signaling molecule that affects numerous critical
functions in the body. There are markedly conflicting findings in the literature regarding the …

Thymoquinone: potential cure for inflammatory disorders and cancer

CC Woo, AP Kumar, G Sethi, KHB Tan - Biochemical pharmacology, 2012 - Elsevier
Thymoquinone is an active ingredient isolated from Nigella sativa and has been
investigated for its anti-oxidant, anti-inflammatory and anticancer activities in both in vitro …

[HTML][HTML] Cancer: Thymoquinone antioxidant/pro-oxidant effect as potential anticancer remedy

YK Mahmoud, HMA Abdelrazek - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Recently, there is growing interest in the natural bioactive components having anticancer
activity. Thymoquinone (TQ), the principle active constituent of black seed (Nigella sativa) …

[HTML][HTML] Therapeutic effects of date fruits (Phoenix dactylifera) in the prevention of diseases via modulation of anti-inflammatory, anti-oxidant and anti-tumour activity

AH Rahmani, SM Aly, H Ali, AY Babiker… - International journal of …, 2014 - ncbi.nlm.nih.gov
The current mode of treatment of various diseases based on synthetic drugs is expensive,
alters genetic and metabolic pathways and also shows adverse side effects. Thus, safe and …

Targeting transcription factor STAT3 for cancer prevention and therapy

EZP Chai, MK Shanmugam, F Arfuso… - Pharmacology & …, 2016 - Elsevier
Abstract Signal Transducers and Activators of Transcription (STATs) comprise an important
class of transcription factors that have been implicated in a wide variety of essential cellular …