Borrelia (Borreliella) burgdorferi, along with closely related species, is the etiologic agent of
Lyme disease. The spirochete subsists in an enzootic cycle that encompasses acquisition …

Infection with Borrelia burgdorferi often triggers pathophysiologic perturbations that are
further augmented by the inflammatory responses of the host, resulting in the severe clinical …

The annual incidence of Lyme disease, caused by tick-transmitted Borreliella burgdorferi, is
estimated to be at least 476,000 cases in the United States and many more worldwide. Ten …

The bacterial pathogen Borrelia burgdorferi is the causative agent of Lyme disease and is
transmitted to humans through an Ixodes tick vector. B. burgdorferi is able to survive in both …

In this study, we examined the relationship between c-di-GMP and its only known effector
protein, PlzA, in Borrelia burgdorferi during the arthropod and mammalian phases of the …

Throughout its enzootic cycle, the Lyme disease spirochete Borreliella (Borrelia) burgdorferi,
senses and responds to changes in its environment using a small repertoire of transcription …

DksA with (p) ppGpp regulates a wide range of gene transcriptions during the stringent
response. The aim of this study was to identify a DksA ortholog in Acinetobacter baumannii …

ABSTRACT bb0616 of Borrelia burgdorferi, the Lyme disease pathogen, encodes a
hypothetical protein of unknown function. In this study, we showed that BB0616 was not …

In Borrelia burgdorferi, BB0556 was annotated as a conserved hypothetical protein. We
herein investigated gene expression and the importance of this protein during infection. Our …

The alternative sigma factor RpoS in Borrelia burgdorferi, the etiological agent of Lyme
disease, has long been postulated to regulate virulence-associated genes other than ospC …