Synthesis and pharmacological activities of pyrazole derivatives: A review
Pyrazole and its derivatives are considered a pharmacologically important active scaffold
that possesses almost all types of pharmacological activities. The presence of this nucleus in …
that possesses almost all types of pharmacological activities. The presence of this nucleus in …
A review on diverse heterocyclic compounds as the privileged scaffolds in antimalarial drug discovery
The upward extend of malaria collectively with the emergence of resistance against
predictable drugs has put enormous pressure on public health systems to introduce new …
predictable drugs has put enormous pressure on public health systems to introduce new …
[HTML][HTML] Pyrazole and pyrazoline derivatives as antimalarial agents: A key review
Malaria poses a severe public health risk and a significant economic burden in disease-
endemic countries. One of the most severe issues in malaria control is the development of …
endemic countries. One of the most severe issues in malaria control is the development of …
The therapeutic voyage of pyrazole and its analogs: a review
Pyrazole, a five membered heteroaromatic ring with two nitrogen atoms is of immense
significance. Presence of this nucleus in the pharmacological agents of diverse therapeutic …
significance. Presence of this nucleus in the pharmacological agents of diverse therapeutic …
Recent advances of pyrazole-containing derivatives as anti-tubercular agents
Z Xu, C Gao, QC Ren, XF Song, LS Feng… - European journal of …, 2017 - Elsevier
One-third of the world's population infected tuberculosis (TB), and more than 1 million
deaths annually. The co-infection between the mainly pathogen Mycobacterium tuberculosis …
deaths annually. The co-infection between the mainly pathogen Mycobacterium tuberculosis …
New progress in azole compounds as antimicrobial agents
HZ Zhang, LL Gan, H Wang… - Mini reviews in medicinal …, 2017 - ingentaconnect.com
The increasing incidence of microbial resistance and newly emerging pathogens have
become a serious challenge for public health. More and more efforts have been directed to …
become a serious challenge for public health. More and more efforts have been directed to …
Synthesis, single crystal, TD-DFT, molecular dynamics simulation and DNA binding studies of carbothioamide analog
In this work, analog 3b (5-(4-(dimethylamino) phenyl)-3-(4-methoxyphenyl)-4, 5-dihydro-1H-
pyrazole-1-carbothioamide) of pyrazoline derivative was produced based on the active site …
pyrazole-1-carbothioamide) of pyrazoline derivative was produced based on the active site …
Design and synthesis of carbothioamide/carboxamide-based pyrazoline analogs as potential anticancer agents: apoptosis, molecular docking, ADME assay, and DNA …
To discover anticancer drugs with novel structures and expand our research scope,
pyrazoline derivatives (3a–3l) were designed and synthesized through cyclization of …
pyrazoline derivatives (3a–3l) were designed and synthesized through cyclization of …
Recent advances in sulfenylation of C (sp3) H bond under transition metal-free conditions
XM Xu, DM Chen, ZL Wang - Chinese Chemical Letters, 2020 - Elsevier
In recent years, the transition metal-free sulfenylation of Csingle bondH bond for Csingle
bondS formation has been rapidly advanced and has become an eco-friendly synthetic tool …
bondS formation has been rapidly advanced and has become an eco-friendly synthetic tool …
Novel morpholinoquinoline nucleus clubbed with pyrazoline scaffolds: Synthesis, antibacterial, antitubercular and antimalarial activities
A series of novel morpholinoquinoline based conjugates with pyrazoline moiety were
synthesized under microwave irradiation. The newly synthesized compounds were …
synthesized under microwave irradiation. The newly synthesized compounds were …