Chemoresistance is a leading cause of morbidity and mortality in cancer and it continues to
be a challenge in cancer treatment. Chemoresistance is influenced by genetic and …

Simple Summary Integrins play key roles in mediating cell adhesion and delivering chemical
and mechanical signals to the interior of the cell. Consequently, they actively control cellular …

There is growing appreciation of the importance of the mechanical properties of the tumor
microenvironment on disease progression. However, the role of extracellular matrix (ECM) …

MicroRNAs play key roles during various crucial cell processes, such as proliferation,
migration, and invasion. In addition, microRNAs have been shown to possess oncogenic …

Background/Aims: Circular RNAs (circRNAs) act as microRNA (miRNA) sponges that
regulate gene expression and are involved in physiological and pathological processes. In …

Human integrin receptors are important for cell-cell and cell-matrix adhesion in normal
epithelial cells. Emerging evidences have indicated integrin members are involved in cancer …

Here we sought to determine the relationship between STAT3 activity and Galectin‐3 (Gal‐
3) and to investigate the cytotoxic effect of PectaSol‐C Modified Citrus Pectin (Pect‐MCP) as …

Intractable human diseases such as cancers, are context dependent, unique to both the
individual patient and to the specific tumor microenvironment. However, conventional cancer …

In vitro 3D culture models have emerged in the cancer field due to their ability to recapitulate
characteristics of the in vivo tumor. Herein, we described the establishment and …

Ovarian cancer is considered to be the most lethal type of gynecological cancer. During the
advanced stages of ovarian cancer, an accumulation of ascites is observed. Fucosylation …