Circulating tumor cells (CTCs) originate from the primary tumor mass and enter into the
peripheral bloodstream. Compared to other “liquid biopsy” portfolios such as exosome …

Importance A significant proportion of patients with early-stage triple-negative breast cancer
(TNBC) are treated with neoadjuvant chemotherapy. Sequencing of circulating tumor DNA …

Many lab-on-a-chip applications require processing of droplets, cells, and particles using
narrow confinements. The physics governing the process of a particle squeezing through …

We report on-chip isolation and detection of circulating tumor cells (CTCs) from blood
samples using a system that integrates a microchip with immunomagnetics, high-throughput …

Early cancer detection, its monitoring, and therapeutical prediction are highly valuable,
though extremely challenging targets in oncology. Significant progress has been made …

As the most promising “liquid biopsy”, analysis of circulating tumor cells (CTCs) provides
noninvasive access to obtain biological information of solid tumors. It not only advances the …

Circulating tumor cells (CTCs) play an essential role in the metastasis of tumors, and thus
can serve as a valuable prognostic factor for malignant diseases. As a result, the ability to …

Current efforts for the detection of prostate cancer using only prostate specific antigen are
not ideal and indicate a need to develop new assays–using multiple targets–that can more …

High gradient magnetic separation is a well-established technology in the mineral
processing industry, and has been used for decades in the bioprocessing industry. Less well …

We report a biosensing method based on magnetic particles where coated magnetic
particles are used for immunomagnetic separation, and uncoated magnetic particles are …