[HTML][HTML] Histone deacetylases and cancer
B Barneda-Zahonero, M Parra - Molecular oncology, 2012 - Elsevier
Reversible acetylation of histone and non-histone proteins is one of the most abundant post-
translational modifications in eukaryotic cells. Protein acetylation and deacetylation are …
translational modifications in eukaryotic cells. Protein acetylation and deacetylation are …
[HTML][HTML] Roles of histone deacetylases in epigenetic regulation: emerging paradigms from studies with inhibitors
The zinc-dependent mammalian histone deacetylase (HDAC) family comprises 11 enzymes,
which have specific and critical functions in development and tissue homeostasis. Mounting …
which have specific and critical functions in development and tissue homeostasis. Mounting …
Structure and function insights into the NuRD chromatin remodeling complex
MP Torchy, A Hamiche, BP Klaholz - Cellular and Molecular Life Sciences, 2015 - Springer
Transcription regulation through chromatin compaction and decompaction is regulated
through various chromatin-remodeling complexes such as nucleosome remodeling and …
through various chromatin-remodeling complexes such as nucleosome remodeling and …
Histone deacetylase function in CD4+ T cells
W Ellmeier, C Seiser - Nature Reviews Immunology, 2018 - nature.com
The differentiation of T helper cell subsets and their acquisition of effector functions are
accompanied by changes in gene expression programmes, which in part are regulated and …
accompanied by changes in gene expression programmes, which in part are regulated and …
The nucleosome remodeling and deacetylase complex in development and disease
J Basta, M Rauchman - Translating epigenetics to the clinic, 2017 - Elsevier
Abstract The Nucleosome Remodeling and Deacetylase (NuRD) complex is one of the
major chromatin remodeling complexes found in cells. It plays an important role in regulating …
major chromatin remodeling complexes found in cells. It plays an important role in regulating …
Histone deacetylases in memory and cognition
Over the past 30 years, lysine acetylation of histone and nonhistone proteins has become
established as a key modulator of gene expression regulating numerous aspects of cell …
established as a key modulator of gene expression regulating numerous aspects of cell …
Targeting histone acetylation in pulmonary hypertension and right ventricular hypertrophy
Epigenetic mechanisms, including DNA methylation and histone post‐translational
modifications (PTMs), have been known to regulate chromatin structure and lineage‐specific …
modifications (PTMs), have been known to regulate chromatin structure and lineage‐specific …
Dysregulated Class I histone deacetylases are indicators of poor prognosis in multiple myeloma
S Mithraprabhu, A Kalff, A Chow, T Khong… - Epigenetics, 2014 - Taylor & Francis
Histone deacetylases (HDAC) control gene expression through their ability to acetylate
proteins, thereby influencing a diverse range of cellular functions. Class I HDAC (HDAC1–3 …
proteins, thereby influencing a diverse range of cellular functions. Class I HDAC (HDAC1–3 …
The nurd architecture
HF Allen, PA Wade, TG Kutateladze - Cellular and Molecular Life Sciences, 2013 - Springer
The nucleosome remodeling and deacetylase (NuRD) complex regulates chromatin
organization, gene transcription, genomic stability and developmental signaling. NuRD has …
organization, gene transcription, genomic stability and developmental signaling. NuRD has …
Crosstalk between phosphorylation and O‐Glc NA cylation: friend or foe
A wide variety of protein post‐translational modifications (PTM s) decorate cellular proteins,
regulating their structure, interactions and ultimately their function. The density of co …
regulating their structure, interactions and ultimately their function. The density of co …