Chronic pain affects one in five of the general population and is the third most important
cause of disability-adjusted life-years globally. Unfortunately, treatment remains inadequate …

The incidence of both type 1 and type 2 diabetes is increasing worldwide. Diabetic
peripheral neuropathy (DPN) is among the most distressing and costly of all the chronic …

Background The major reasons to treat sarcoidosis are to lower the morbidity and mortality
risk or to improve quality of life (QoL). The indication for treatment varies depending on …

Abstract Background and Purpose In these guidelines, we aimed to develop evidence‐
based recommendations for the use of screening questionnaires and diagnostic tests in …

There are potentially many ways of assessing diabetic peripheral neuropathy (DPN).
However, they do not fulfill US Food and Drug Administration (FDA) requirements in relation …

Aims/hypothesis Corneal confocal microscopy is a rapid non-invasive ophthalmic imaging
technique that identifies peripheral and central neurodegenerative disease. Quantification of …

Significant advances have been made in the potential and accuracy of diagnostics for
neurosarcoidosis. Treatment should be approached within the context of the patient's …

Purpose Diagnosing early diabetic peripheral neuropathy remains a challenge due to
deficiencies in currently advocated end points. The cornea is densely innervated with small …

Nerve conduction studies (NCS) are an essential aspect of the assessment of patients with
peripheral neuropathies. However, conventional NCS do not reflect activation of small …

Purpose To evaluate in vivo confocal microscopy (IVCM) features of corneal subbasal nerve
plexus (SNP) in the setting of dry eye disease (DED) using fully automated software …