Chemical and pharmacological aspects of caffeic acid and its activity in hepatocarcinoma

KMM Espíndola, RG Ferreira, LEM Narvaez… - Frontiers in …, 2019 - frontiersin.org
Caffeic acid (CA) is a phenolic compound synthesized by all plant species and is present in
foods such as coffee, wine, tea, and popular medicines such as propolis. This phenolic acid …

Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses

LN Vandenberg, T Colborn, TB Hayes… - Endocrine …, 2012 - academic.oup.com
For decades, studies of endocrine-disrupting chemicals (EDCs) have challenged traditional
concepts in toxicology, in particular the dogma of “the dose makes the poison,” because …

Dietary flavonoids: effects on xenobiotic and carcinogen metabolism

YJ Moon, X Wang, ME Morris - Toxicology in vitro, 2006 - Elsevier
Flavonoids are present in fruits, vegetables and beverages derived from plants (tea, red
wine), and in many dietary supplements or herbal remedies including Ginkgo Biloba, Soy …

Phytoestrogens and their human metabolites show distinct agonistic and antagonistic properties on estrogen receptor α (ERα) and ERβ in human cells

SO Mueller, S Simon, K Chae, M Metzler… - Toxicological …, 2004 - academic.oup.com
Phytoestrogens exert pleiotropic effects on cellular signaling and show some beneficial
effects on estrogen-dependent diseases. However, due to activation/inhibition of the …

Soy, phytoestrogens and their impact on reproductive health

CR Cederroth, C Zimmermann, S Nef - Molecular and cellular …, 2012 - Elsevier
There is growing interest in the potential health threats posed by endocrine-disrupting
chemicals (EDCs) to the reproductive system. Soybean is the most important dietary source …

[PDF][PDF] The physiological actions of isoflavone phytoestrogens

L Pilšáková, I Riečanský, F Jagla - Physiol Res, 2010 - academia.edu
Isoflavones are a subgroup of phytoestrogens, natural plant substances with structure
similar to 17-β-estradiol and capable of binding to estrogen receptors (ERs). Isoflavones …

Interference of endocrine disrupting chemicals with aromatase CYP19 expression or activity, and consequences for reproduction of teleost fish

K Cheshenko, F Pakdel, H Segner, O Kah… - General and comparative …, 2008 - Elsevier
Many natural and synthetic compounds present in the environment exert a number of
adverse effects on the exposed organisms, leading to endocrine disruption, for which they …

Potential therapeutic applications of some antinutritional plant secondary metabolites

B Singh, TK Bhat, B Singh - Journal of Agricultural and Food …, 2003 - ACS Publications
Plant-based formulations have been used since ancient times as remedial measures
against various human and animal ailments. Over the past 20 years interest in traditional …

Is human fecundity declining?

NE Skakkebæk, N Jørgensen, KM Main… - … journal of andrology, 2006 - Wiley Online Library
The decreasing trends in fertility rates in many industrialized countries are now so dramatic
that they deserve much more scientific attention. Although social and behavioural factors …

Contamination of vegetables of different seasons with organophosphorous pesticides and related health risk assessment in northern India

M Bhanti, A Taneja - Chemosphere, 2007 - Elsevier
India is an agrarian country. The use of pesticides, herbicides and fungicides were
introduced in India during the mid-sixties, which are now being used on a large scale and is …