Eukaryotic systematics: a user's guide for cell biologists and parasitologists
Single-celled parasites like Entamoeba, Trypanosoma, Phytophthora and Plasmodium
wreak untold havoc on human habitat and health. Understanding the position of the various …
wreak untold havoc on human habitat and health. Understanding the position of the various …
Antigenic variation in African trypanosomes: the importance of chromosomal and nuclear context in VSG expression control
African trypanosomes are lethal human and animal parasites that use antigenic variation for
evasion of host adaptive immunity. To facilitate antigenic variation, trypanosomes dedicate …
evasion of host adaptive immunity. To facilitate antigenic variation, trypanosomes dedicate …
Kingdoms Protozoa and Chromista and the eozoan root of the eukaryotic tree
T Cavalier-Smith - Biology letters, 2010 - royalsocietypublishing.org
I discuss eukaryotic deep phylogeny and reclassify the basal eukaryotic kingdom Protozoa
and derived kingdom Chromista in the light of multigene trees. I transfer the formerly …
and derived kingdom Chromista in the light of multigene trees. I transfer the formerly …
Origin of the cell nucleus, mitosis and sex: roles of intracellular coevolution
T Cavalier-Smith - Biology direct, 2010 - Springer
Background The transition from prokaryotes to eukaryotes was the most radical change in
cell organisation since life began, with the largest ever burst of gene duplication and novelty …
cell organisation since life began, with the largest ever burst of gene duplication and novelty …
Genome-wide analysis reveals extensive functional interaction between DNA replication initiation and transcription in the genome of Trypanosoma brucei
Identification of replication initiation sites, termed origins, is a crucial step in understanding
genome transmission in any organism. Transcription of the Trypanosoma brucei genome is …
genome transmission in any organism. Transcription of the Trypanosoma brucei genome is …
Leishmania amazonensis Arginase Compartmentalization in the Glycosome Is Important for Parasite Infectivity
In Leishmania, de novo polyamine synthesis is initiated by the cleavage of L-arginine to
urea and L-ornithine by the action of arginase (ARG, EC 3.5. 3.1). Previous studies in L …
urea and L-ornithine by the action of arginase (ARG, EC 3.5. 3.1). Previous studies in L …
Mitochondrial preprotein translocase of trypanosomatids has a bacterial origin
Mitochondria are found in all eukaryotic cells and derive from a bacterial endosymbiont [1,
2]. The evolution of a protein import system was a prerequisite for the conversion of the …
2]. The evolution of a protein import system was a prerequisite for the conversion of the …
Evolution of metabolic capabilities and molecular features of diplonemids, kinetoplastids, and euglenids
Abstract Background The Euglenozoa are a protist group with an especially rich history of
evolutionary diversity. They include diplonemids, representing arguably the most species …
evolutionary diversity. They include diplonemids, representing arguably the most species …
H2B.V demarcates divergent strand-switch regions, some tDNA loci, and genome compartments in Trypanosoma cruzi and affects parasite differentiation and host …
JN Rosón, MO Vitarelli, HM Costa-Silva… - PLoS …, 2022 - journals.plos.org
Histone variants play a crucial role in chromatin structure organization and gene expression.
Trypanosomatids have an unusual H2B variant (H2B. V) that is known to dimerize with the …
Trypanosomatids have an unusual H2B variant (H2B. V) that is known to dimerize with the …
PPL2 translesion polymerase is essential for the completion of chromosomal DNA replication in the African trypanosome
Faithful copying of the genome is essential for life. In eukaryotes, a single archaeo-
eukaryotic primase (AEP), DNA primase, is required for the initiation and progression of …
eukaryotic primase (AEP), DNA primase, is required for the initiation and progression of …