[HTML][HTML] The interaction between the gut microbiota and herbal medicines

X An, Q Bao, S Di, Y Zhao, S Zhao, H Zhang… - Biomedicine & …, 2019 - Elsevier
As technologies used to study the gut microbiota have improved, the relationship between
the gut microbiota and health has become increasingly obvious. Herbal medicines have …

Assessment of herbal medicinal products: challenges, and opportunities to increase the knowledge base for safety assessment

SA Jordan, DG Cunningham, RJ Marles - Toxicology and applied …, 2010 - Elsevier
Although herbal medicinal products (HMP) have been perceived by the public as relatively
low risk, there has been more recognition of the potential risks associated with this type of …

Serum and urine metabolite profiling reveals potential biomarkers of human hepatocellular carcinoma

T Chen, G Xie, X Wang, J Fan, Y Qiu, X Zheng… - Molecular & Cellular …, 2011 - ASBMB
Hepatocellular carcinoma (HCC) is a common malignancy in the world with high morbidity
and mortality rate. Identification of novel biomarkers in HCC remains impeded primarily …

Serum metabolite profiling of human colorectal cancer using GC− TOFMS and UPLC− QTOFMS

Y Qiu, G Cai, M Su, T Chen, X Zheng, Y Xu… - Journal of proteome …, 2009 - ACS Publications
Colorectal carcinogenesis involves the overexpression of many immediate-early response
genes associated with growth and inflammation, which significantly alters downstream …

Plant metabolomics: from holistic data to relevant biomarkers

JL Wolfender, S Rudaz, Y Hae Choi… - Current medicinal …, 2013 - ingentaconnect.com
Metabolomics is playing an increasingly important role in plant science. It aims at the
comprehensive analysis of the plant metabolome which consists both of primary and …

Salivary metabolite signatures of oral cancer and leukoplakia

J Wei, G Xie, Z Zhou, P Shi, Y Qiu… - … journal of cancer, 2011 - Wiley Online Library
Oral cancer, one of the six most common human cancers with an overall 5‐year survival rate
of< 50%, is often not diagnosed until it has reached an advanced stage. The aim of the …

Metabolomics analysis reveals the association between lipid abnormalities and oxidative stress, inflammation, fibrosis and Nrf2 dysfunction in aristolochic acid …

YY Zhao, HL Wang, XL Cheng, F Wei, X Bai, RC Lin… - Scientific reports, 2015 - nature.com
Alternative medicines are commonly used for the disease prevention and treatment
worldwide. Aristolochic acid (AAI) nephropathy (AAN) is a common and rapidly progressive …

Gas chromatography/mass spectrometry in metabolic profiling of biological fluids

KK Pasikanti, PC Ho, ECY Chan - Journal of Chromatography B, 2008 - Elsevier
One of the objectives of metabonomics is to identify subtle changes in metabolite profiles
between biological systems of different physiological or pathological states. Gas …

Discovery of metabolomics biomarkers for early detection of nephrotoxicity

KJ Boudonck, MW Mitchell, L Német… - Toxicologic …, 2009 - journals.sagepub.com
Drug-induced nephrotoxicity is a major concern, since many pharmacological compounds
are filtered through the kidneys for excretion into urine. To discover biochemical biomarkers …

Current trends and future requirements for the mass spectrometric investigation of microbial, mammalian and plant metabolomes

WB Dunn - Physical biology, 2008 - iopscience.iop.org
The functional levels of biological cells or organisms can be separated into the genome,
transcriptome, proteome and metabolome. Of these the metabolome offers specific …