[PDF][PDF] RETRACTED ARTICLE: Potential of solid dispersions to enhance solubility, bioavailability, and therapeutic efficacy of poorly water-soluble drugs: newer …
S Alshehri, SS Imam, A Hussain, MA Altamimi… - Drug …, 2020 - Taylor & Francis
Abstract We, the Editors and Publisher of Drug Delivery have retracted the following article:
Sultan Alshehri, Syed Sarim Imam, Afzal Hussain, Mohammad A. Altamimi, Nabil K …
Sultan Alshehri, Syed Sarim Imam, Afzal Hussain, Mohammad A. Altamimi, Nabil K …
Quality-by-design in hot melt extrusion based amorphous solid dispersions: An industrial perspective on product development
An industrially feasible approach to overcome the solubility and bioavailability limitations of
poorly soluble active pharmaceutical ingredients is the development of amorphous solid …
poorly soluble active pharmaceutical ingredients is the development of amorphous solid …
Enhanced dissolution of luteolin by solid dispersion prepared by different methods: physicochemical characterization and antioxidant activity
S Alshehri, SS Imam, MA Altamimi, A Hussain… - ACS …, 2020 - ACS Publications
Luteolin (LT) is a poorly soluble bioactive compound that suffered bioavailability problems
after oral administration. Hence, the aim of the proposed research work was to formulate and …
after oral administration. Hence, the aim of the proposed research work was to formulate and …
Selective Laser Sintering of Solid Oral Dosage Forms with Copovidone and Paracetamol Using a CO2 Laser
YA Gueche, NM Sanchez-Ballester, B Bataille… - Pharmaceutics, 2021 - mdpi.com
Material suitability needs to be considered for the 3D printing of solid oral dosage forms
(SODFs). This work aims to assess the suitability of a CO2 laser (λ= 10.6 μm) for selective …
(SODFs). This work aims to assess the suitability of a CO2 laser (λ= 10.6 μm) for selective …
Physicochemical properties of poly-vinyl polymers and their influence on ketoprofen amorphous solid dispersion performance: a polymer selection case study
When developing an amorphous solid dispersion (ASD), a prudent choice of polymer is
critical to several aspects of ASD performance including: processability, solid state stability …
critical to several aspects of ASD performance including: processability, solid state stability …
[HTML][HTML] Dissolution changes in drug-amino acid/biotin co-amorphous systems: decreased/increased dissolution during storage without recrystallization
Z Zou, Q Huang, X Li, X Liu, L Yin, Y Zhao… - European Journal of …, 2023 - Elsevier
Co-amorphous systems have been proven to be a promising strategy to address the poor
water solubility of poorly water-soluble drugs. Generally, the initial dissolution behaviors …
water solubility of poorly water-soluble drugs. Generally, the initial dissolution behaviors …
Solubility enhanced formulation approaches to overcome oral delivery obstacles of PROTACs
F Pöstges, K Kayser, J Appelhaus, M Monschke… - Pharmaceutics, 2023 - mdpi.com
PROteolysis TArgeting Chimaeras (PROTACs) offer new opportunities in modern medicine
by targeting proteins that are undruggable to classic inhibitors. However, due to their …
by targeting proteins that are undruggable to classic inhibitors. However, due to their …
A Fisetin Delivery System for Neuroprotection: A Co-Amorphous Dispersion Prepared in Supercritical Carbon Dioxide
Fisetin (FIS), a senolytic flavonoid, mitigates age-related neuroprotective changes. An
amorphous FIS dispersion with a co-carrier was prepared using supercritical fluid extraction …
amorphous FIS dispersion with a co-carrier was prepared using supercritical fluid extraction …
Amorphous System of Hesperetin and Piperine—Improvement of Apparent Solubility, Permeability, and Biological Activities
K Wdowiak, A Miklaszewski, R Pietrzak… - International Journal of …, 2023 - mdpi.com
The low bioaccessibility of hesperetin and piperine hampers their application as therapeutic
agents. Piperine has the ability to improve the bioavailability of many compounds when co …
agents. Piperine has the ability to improve the bioavailability of many compounds when co …
Binary polymeric amorphous carvedilol solid dispersions: In vitro and in vivo characterization
M Krstić, L Manić, N Martić, D Vasiljević… - European Journal of …, 2020 - Elsevier
Binary polymeric amorphous carvedilol solid dispersions were prepared using solvent
method by varying solvent type, polymer type and carvedilol to polymer ratio in order to …
method by varying solvent type, polymer type and carvedilol to polymer ratio in order to …