[HTML][HTML] 5-Fluorouracil (5-FU) resistance and the new strategy to enhance the sensitivity against cancer: Implication of DNA repair inhibition

C Sethy, CN Kundu - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Fluorouracil (5-FU) has been an important anti-cancer drug to date. With an increase in the
knowledge of its mechanism of action, various treatment modalities have been developed …

Nanoparticles in dentistry: A comprehensive review

G Moraes, C Zambom, WL Siqueira - Pharmaceuticals, 2021 - mdpi.com
In recent years, nanoparticles (NPs) have been receiving more attention in dentistry. Their
advantageous physicochemical and biological properties can improve the diagnosis …

Nano-drug delivery systems in oral cancer therapy: recent developments and prospective

Y Zhang, Y Wu, H Du, Z Li, X Bai, Y Wu, H Li, M Zhou… - Pharmaceutics, 2023 - mdpi.com
Oral cancer (OC), characterized by malignant tumors in the mouth, is one of the most
prevalent malignancies worldwide. Chemotherapy is a commonly used treatment for OC; …

[HTML][HTML] UMAOH calcium phosphate coatings designed for drug delivery: Vancomycin, 5-fluorouracil, interferon α-2b case

KA Prosolov, EG Komarova, EA Kazantseva… - Materials, 2022 - mdpi.com
Drug delivery systems based on calcium phosphate (CaP) coatings have been recently
recognized as beneficial drug delivery systems in complex cases of bone diseases for …

Nanoparticles as drug delivery systems in the treatment of oral squamous cell carcinoma: current status and recent progression

S Cui, H Liu, G Cui - Frontiers in Pharmacology, 2023 - frontiersin.org
Oral squamous cell carcinoma (OSCC) is a common human malignancy with an estimated
incidence of around 377,713 new cases worldwide in 2020. Despite the advance in clinical …

Phytochemical screening and in-vitro antibacterial and anticancer activity of crude extract of Matricaria aurea

I Ahmad, MA Mir, S Srivastava, AA Shati… - Current …, 2021 - ingentaconnect.com
Background: Infectious diseases constantly represent the source of sickness as well as
mortality in human beings. Herbal applications in human life through using plants for …

Surface decoration of PLGA nanoparticles enables efficient transport of floxuridine oligomers into mammalian cells

L Barnaud, S Fukuhara, M Pava, M Carrasco… - Reactive and Functional …, 2024 - Elsevier
deoxy-5-fluorouridine (Floxuridine, FdU) oligomers are repeated FdU residues linked to
each other through phosphate groups exhibiting anticancer properties. One of the major …

Transforming Cancer Care: Immunotherapy with Advanced Drug Delivery

S Srivastava, TC Siang, D Kaliyappan… - Journal of Drug Delivery …, 2024 - Elsevier
This study investigates the integration of immunotherapeutic agents into various drug
delivery platforms for cancer treatment, emphasizing their efficacy in diverse cancer types …

The prospects of nanotherapeutic approaches for targeting tumor-associated macrophages in oral cancer

D Bhattacharya, K Sakhare, KP Narayan… - … , Biology and Medicine, 2021 - Elsevier
OSCC (oral squamous cell carcinoma) is currently one of the most formidable cancers
plagued by challenges like low overall survivability, lymph node associated metastasis, drug …

Controlled anticancer 5-Fluorouracil release from functionalized 5-FU/PLGA/CaP coating on titanium implants: Characterization, in vitro drug delivery and cytotoxicity

EG Komarova, EI Senkina, AS Lozhkomoev… - Materials Today …, 2024 - Elsevier
Work presents a novel approach for creating anticancer coatings on titanium implants using
5-Fluorouracil (5-FU) loaded in calcium phosphate which is encapsulated in poly (lactic-co …