Despite the long-standing belief in the analgesic properties of alcohol, experimental studies
have produced mixed results. This meta-analysis aimed to clarify whether alcohol produces …

Introduction Chronic pain represents a global health problem with a considerable economic
burden. The relation of alcohol intake and chronic pain conditions was assessed in several …

Alcohol use disorder (AUD) and chronic pain are enduring and devastating conditions that
share an intersecting epidemiology and neurobiology. Chronic alcohol use itself can …

Abstract Background and Purpose Chronic pain is considered a key factor contributing to
alcohol use disorder (AUD). The mechanisms responsible for chronic pain associated with …

Chronic pain (CP) is a common and often debilitating disorder that has major social and
economic impacts. A subset of patients develop CP that significantly interferes with their …

Epidemiological data indicate a strong association between alcohol use disorder (AUD) and
neuropathic pain. Genetically-selected Marchigian Sardinian alcohol-preferring (msP) rats …

Alcohol is an effective and widely utilized analgesic. However, the chronic use of alcohol
can actually facilitate nociceptive sensitivity over time, a condition known as hyperalgesia …

Introduction The clinical influence of smoking cessation on pain tolerance before surgery
and postoperative pain perception is not fully understood. This clinical study investigated the …

Inflammation is linked with chronic pain but the extent to which this relationship is associated
with biopsychosocial factors is not known. We investigated relationships between blood C …

Background Central sensitization is an important mechanism underlying many chronic pain
conditions. Chronic pain and alcohol use disorder (AUD) are highly comorbid. Despite great …