[HTML][HTML] Polymer bioconjugates: Modern design concepts toward precision hybrid materials
The conjugation of synthetic polymers with various biomolecules provides an easy access to
biohybrid materials which combine advantages from both the synthetic world and Nature …
biohybrid materials which combine advantages from both the synthetic world and Nature …
Multivalent glycoconjugates as anti-pathogenic agents
A Bernardi, J Jiménez-Barbero, A Casnati… - Chemical Society …, 2013 - pubs.rsc.org
Multivalency plays a major role in biological processes and particularly in the relationship
between pathogenic microorganisms and their host that involves protein–glycan recognition …
between pathogenic microorganisms and their host that involves protein–glycan recognition …
Therapeutic protein–polymer conjugates: advancing beyond PEGylation
EM Pelegri-O'Day, EW Lin… - Journal of the American …, 2014 - ACS Publications
Protein–polymer conjugates are widely used as therapeutics. All Food and Drug
Administration (FDA)-approved protein conjugates are covalently linked to poly (ethylene …
Administration (FDA)-approved protein conjugates are covalently linked to poly (ethylene …
Dendrimers in biomedical applications—reflections on the field
S Svenson, DA Tomalia - Advanced drug delivery reviews, 2012 - Elsevier
The formation of particulate systems with well-defined sizes and shapes is of eminent
interest in certain medical applications such as drug delivery, gene transfection, and …
interest in certain medical applications such as drug delivery, gene transfection, and …
Designing dendrimers for biological applications
Dendrimers are branched, synthetic polymers with layered architectures that show promise
in several biomedical applications. By regulating dendrimer synthesis, it is possible to …
in several biomedical applications. By regulating dendrimer synthesis, it is possible to …
Glycoprotein synthesis: an update
DP Gamblin, EM Scanlan, BG Davis - Chemical Reviews, 2009 - ACS Publications
1.1 Aims This review updates our original review on the synthesis of glycoproteins.(1) Its
aims, therefore, are 2-fold: to highlight, first, key developments since 2002 and, second …
aims, therefore, are 2-fold: to highlight, first, key developments since 2002 and, second …
Synthesis of N-acyl sulfenamides via copper catalysis and their use as S-sulfenylating reagents of thiols
Z Bai, S Zhu, Y Hu, P Yang, X Chu, G He… - Nature …, 2022 - nature.com
Sulfur–heteroatom bonds such as S–S and S–N are found in a variety of natural products
and often play important roles in biological processes. Despite their widespread …
and often play important roles in biological processes. Despite their widespread …
A “tag-and-modify” approach to site-selective protein modification
JM Chalker, GJL Bernardes… - Accounts of chemical …, 2011 - ACS Publications
Covalent modification can expand a protein's functional capacity. Fluorescent or radioactive
labeling, for instance, allows imaging of a protein in real time. Labeling with an affinity probe …
labeling, for instance, allows imaging of a protein in real time. Labeling with an affinity probe …
Visual observation of the mercury-stimulated peroxidase mimetic activity of gold nanoparticles
YJ Long, YF Li, Y Liu, JJ Zheng, J Tang… - Chemical …, 2011 - pubs.rsc.org
Visual observation of the mercury-stimulated peroxidase mimetic activity of gold nanoparticles -
Chemical Communications (RSC Publishing) DOI:10.1039/C1CC14294A Royal Society of …
Chemical Communications (RSC Publishing) DOI:10.1039/C1CC14294A Royal Society of …
Glycotherapy: new advances inspire a reemergence of glycans in medicine
JE Hudak, CR Bertozzi - Chemistry & biology, 2014 - cell.com
The beginning of the 20 th century marked the dawn of modern medicine with glycan-based
therapies at the forefront. However, glycans quickly became overshadowed as DNA-and …
therapies at the forefront. However, glycans quickly became overshadowed as DNA-and …