[HTML][HTML] Polymer bioconjugates: Modern design concepts toward precision hybrid materials

C Chen, DYW Ng, T Weil - Progress in Polymer Science, 2020 - Elsevier
The conjugation of synthetic polymers with various biomolecules provides an easy access to
biohybrid materials which combine advantages from both the synthetic world and Nature …

Multivalent glycoconjugates as anti-pathogenic agents

A Bernardi, J Jiménez-Barbero, A Casnati… - Chemical Society …, 2013 - pubs.rsc.org
Multivalency plays a major role in biological processes and particularly in the relationship
between pathogenic microorganisms and their host that involves protein–glycan recognition …

Therapeutic protein–polymer conjugates: advancing beyond PEGylation

EM Pelegri-O'Day, EW Lin… - Journal of the American …, 2014 - ACS Publications
Protein–polymer conjugates are widely used as therapeutics. All Food and Drug
Administration (FDA)-approved protein conjugates are covalently linked to poly (ethylene …

Dendrimers in biomedical applications—reflections on the field

S Svenson, DA Tomalia - Advanced drug delivery reviews, 2012 - Elsevier
The formation of particulate systems with well-defined sizes and shapes is of eminent
interest in certain medical applications such as drug delivery, gene transfection, and …

Designing dendrimers for biological applications

CC Lee, JA MacKay, JMJ Fréchet, FC Szoka - Nature biotechnology, 2005 - nature.com
Dendrimers are branched, synthetic polymers with layered architectures that show promise
in several biomedical applications. By regulating dendrimer synthesis, it is possible to …

Glycoprotein synthesis: an update

DP Gamblin, EM Scanlan, BG Davis - Chemical Reviews, 2009 - ACS Publications
1.1 Aims This review updates our original review on the synthesis of glycoproteins.(1) Its
aims, therefore, are 2-fold: to highlight, first, key developments since 2002 and, second …

Synthesis of N-acyl sulfenamides via copper catalysis and their use as S-sulfenylating reagents of thiols

Z Bai, S Zhu, Y Hu, P Yang, X Chu, G He… - Nature …, 2022 - nature.com
Sulfur–heteroatom bonds such as S–S and S–N are found in a variety of natural products
and often play important roles in biological processes. Despite their widespread …

A “tag-and-modify” approach to site-selective protein modification

JM Chalker, GJL Bernardes… - Accounts of chemical …, 2011 - ACS Publications
Covalent modification can expand a protein's functional capacity. Fluorescent or radioactive
labeling, for instance, allows imaging of a protein in real time. Labeling with an affinity probe …

Visual observation of the mercury-stimulated peroxidase mimetic activity of gold nanoparticles

YJ Long, YF Li, Y Liu, JJ Zheng, J Tang… - Chemical …, 2011 - pubs.rsc.org
Visual observation of the mercury-stimulated peroxidase mimetic activity of gold nanoparticles -
Chemical Communications (RSC Publishing) DOI:10.1039/C1CC14294A Royal Society of …

Glycotherapy: new advances inspire a reemergence of glycans in medicine

JE Hudak, CR Bertozzi - Chemistry & biology, 2014 - cell.com
The beginning of the 20 th century marked the dawn of modern medicine with glycan-based
therapies at the forefront. However, glycans quickly became overshadowed as DNA-and …