Efficient and reliable amplification of chirality has borne its greatest fruit with transition metal-
catalyzed reactions since enantiocontrol may often be imposed by replacing an achiral or …

Organic chemists have always been fascinated by the cyclopropane subunit. 1 The smallest
cycloalkane is found as a basic structural element in a wide range of naturally occurring …

R-amino acid reductions, allow entry to other classes of compounds that are also useful as
the source of chiral centers, as with R-amino aldehydes, that, in turn, can be used in a …

Catalytic Asymmetric Synthesis Seminal text presenting detailed accounts of the most
important catalytic asymmetric reactions known today This book covers the preparation of …

The discovery and development of new chemical reactions is a major focus of research
activity in organic chemistry. The chemical synthesis of molecules provided by Nature has …

Asymmetric catalysis with chiral metal complexes has received considerable attention in
recent years, and its contribution to the art of organic synthesis has become of leading …

The preparation of new enantiopure ligands that provide a chiral environment to metals so
that they perform efficient asymmetric catalysis is one of the most straightforward challenges …

2-Oxazolines have permeated numerous sub-disciplines in synthetic organic chemistry in
the 100 years since their discovery. This versatile heterocycle has served as protecting …

The rhodium N-(arylsulfonyl) prolinate catalyzed decomposition of vinyldiazomethanes in
the presence of alkenes leads to a very general method for the synthesis of functionalized …

In order to replace a substituent at a single stereogenic center of a chiral molecule without
racemization, a temporary center of chirality is first generated diastereoselectively, the …