Potassium channels in cell cycle and cell proliferation
D Urrego, AP Tomczak, F Zahed… - … of the Royal …, 2014 - royalsocietypublishing.org
Normal cell-cycle progression is a crucial task for every multicellular organism, as it
determines body size and shape, tissue renewal and senescence, and is also crucial for …
determines body size and shape, tissue renewal and senescence, and is also crucial for …
Mitochondrial dynamics and mitophagy in lung disorders
Mitochondria are biosynthetic, bioenergetic, and signaling organelles which are critical for
physiological adaptations and cellular stress responses to the environment. Various …
physiological adaptations and cellular stress responses to the environment. Various …
Dynamic shaping of cellular membranes by phospholipids and membrane-deforming proteins
S Suetsugu, S Kurisu, T Takenawa - Physiological reviews, 2014 - journals.physiology.org
All cellular compartments are separated from the external environment by a membrane,
which consists of a lipid bilayer. Subcellular structures, including clathrin-coated pits …
which consists of a lipid bilayer. Subcellular structures, including clathrin-coated pits …
Phospholipase D signaling pathways and phosphatidic acid as therapeutic targets in cancer
RC Bruntz, CW Lindsley, HA Brown - Pharmacological reviews, 2014 - ASPET
Phospholipase D is a ubiquitous class of enzymes that generates phosphatidic acid as an
intracellular signaling species. The phospholipase D superfamily plays a central role in a …
intracellular signaling species. The phospholipase D superfamily plays a central role in a …
Feedback regulation between plasma membrane tension and membrane-bending proteins organizes cell polarity during leading edge formation
K Tsujita, T Takenawa, T Itoh - Nature cell biology, 2015 - nature.com
Tension applied to the plasma membrane (PM) is a global mechanical parameter involved
in cell migration. However, how membrane tension regulates actin assembly is unknown …
in cell migration. However, how membrane tension regulates actin assembly is unknown …
Understanding of the roles of phospholipase D and phosphatidic acid through their binding partners
Phospholipase D (PLD) is a phosphatidyl choline (PC)-hydrolyzing enzyme that generates
phosphatidic acid (PA), a lipid second messenger that modulates diverse intracellular …
phosphatidic acid (PA), a lipid second messenger that modulates diverse intracellular …
Role of mitochondrial lipids in guiding fission and fusion
MA Frohman - Journal of molecular medicine, 2015 - Springer
Clinically important links have been established between mitochondrial function and cardiac
physiology and disease in the context of signaling mechanisms, energy production, and …
physiology and disease in the context of signaling mechanisms, energy production, and …
Dendritic spine initiation in brain development, learning and diseases and impact of BAR-domain proteins
P Khanal, P Hotulainen - Cells, 2021 - mdpi.com
Dendritic spines are small, bulbous protrusions along neuronal dendrites where most of the
excitatory synapses are located. Dendritic spine density in normal human brain increases …
excitatory synapses are located. Dendritic spine density in normal human brain increases …
New era of diacylglycerol kinase, phosphatidic acid and phosphatidic acid-binding protein
F Sakane, F Hoshino, C Murakami - International journal of molecular …, 2020 - mdpi.com
Diacylglycerol kinase (DGK) phosphorylates diacylglycerol (DG) to generate phosphatidic
acid (PA). Mammalian DGK consists of ten isozymes (α–κ) and governs a wide range of …
acid (PA). Mammalian DGK consists of ten isozymes (α–κ) and governs a wide range of …
Phospholipase D (PLD) drives cell invasion, tumor growth and metastasis in a human breast cancer xenograph model
KM Henkels, GP Boivin, ES Dudley, SJ Berberich… - Oncogene, 2013 - nature.com
Breast cancer is one of the most common malignancies in human females in the world. One
protein that has elevated enzymatic lipase activity in breast cancers in vitro is phospholipase …
protein that has elevated enzymatic lipase activity in breast cancers in vitro is phospholipase …