The plant Cannabis sativa L. has been used as an herbal remedy for centuries and is the
most important source of phytocannabinoids. The endocannabinoid system (ECS) consists …

The term'endocannabinoid'—originally coined in the mid-1990s after the discovery of
membrane receptors for the psychoactive principle in Cannabis, Δ9-tetrahydrocannabinol …

Neurodegeneration leading to Parkinson's disease (PD) and Alzheimer's disease (AD) has
become a major health burden globally. Current treatments mainly target controlling …

Cannabinoids—the active components of Cannabis sativa and their derivatives—exert
palliative effects in cancer patients by preventing nausea, vomiting and pain and by …

Rationale Phytocannabinoids are useful therapeutics for multiple applications including
treatments of constipation, malaria, rheumatism, alleviation of intraocular pressure, emesis …

Intrapartum-related events are the third leading cause of childhood mortality worldwide and
result in one million neurodisabled survivors each year. Infants exposed to a perinatal insult …

After the discovery, in the early 1990s, of specific G‐protein‐coupled receptors for
marijuana's psychoactive principle Δ9‐tetrahydrocannabinol, the cannabinoid receptors …

In the postnatal brain, endocannabinoids acting as retrograde messengers regulate the
function of many synapses. By contrast, the understanding of endocannabinoid functions …

The endocannabinoid signalling system includes:(1) at least two G-protein-coupled
receptors, known as the cannabinoid CB1 and CB2 receptors and discovered following …

CB1 receptors are G-protein coupled receptors (GPCRs) abundant in neurons, in which they
modulate neurotransmission. The CB1 receptor influence on memory and learning is well …